Cargando…
The Metabolism and Immune Environment in Diffuse Large B-Cell Lymphoma
Cells utilize different metabolic processes to maintain their growth and differentiation. Tumor cells have made some metabolic changes to protect themselves from malnutrition. These metabolic alterations affect the tumor microenvironment and macroenvironment. Developing drugs targeting these metabol...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300995/ https://www.ncbi.nlm.nih.gov/pubmed/37367892 http://dx.doi.org/10.3390/metabo13060734 |
_version_ | 1785064707873308672 |
---|---|
author | Wu, Jianbo Meng, Fuqing Ran, Danyang Song, Yalong Dang, Yunkun Lai, Fan Yang, Longyan Deng, Mi Song, Yuqin Zhu, Jun |
author_facet | Wu, Jianbo Meng, Fuqing Ran, Danyang Song, Yalong Dang, Yunkun Lai, Fan Yang, Longyan Deng, Mi Song, Yuqin Zhu, Jun |
author_sort | Wu, Jianbo |
collection | PubMed |
description | Cells utilize different metabolic processes to maintain their growth and differentiation. Tumor cells have made some metabolic changes to protect themselves from malnutrition. These metabolic alterations affect the tumor microenvironment and macroenvironment. Developing drugs targeting these metabolic alterations could be a good direction. In this review, we briefly introduce metabolic changes/regulations of the tumor macroenvironment and microenvironment and summarize potential drugs targeting the metabolism in diffuse large B-cell lymphoma. |
format | Online Article Text |
id | pubmed-10300995 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-103009952023-06-29 The Metabolism and Immune Environment in Diffuse Large B-Cell Lymphoma Wu, Jianbo Meng, Fuqing Ran, Danyang Song, Yalong Dang, Yunkun Lai, Fan Yang, Longyan Deng, Mi Song, Yuqin Zhu, Jun Metabolites Review Cells utilize different metabolic processes to maintain their growth and differentiation. Tumor cells have made some metabolic changes to protect themselves from malnutrition. These metabolic alterations affect the tumor microenvironment and macroenvironment. Developing drugs targeting these metabolic alterations could be a good direction. In this review, we briefly introduce metabolic changes/regulations of the tumor macroenvironment and microenvironment and summarize potential drugs targeting the metabolism in diffuse large B-cell lymphoma. MDPI 2023-06-08 /pmc/articles/PMC10300995/ /pubmed/37367892 http://dx.doi.org/10.3390/metabo13060734 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Wu, Jianbo Meng, Fuqing Ran, Danyang Song, Yalong Dang, Yunkun Lai, Fan Yang, Longyan Deng, Mi Song, Yuqin Zhu, Jun The Metabolism and Immune Environment in Diffuse Large B-Cell Lymphoma |
title | The Metabolism and Immune Environment in Diffuse Large B-Cell Lymphoma |
title_full | The Metabolism and Immune Environment in Diffuse Large B-Cell Lymphoma |
title_fullStr | The Metabolism and Immune Environment in Diffuse Large B-Cell Lymphoma |
title_full_unstemmed | The Metabolism and Immune Environment in Diffuse Large B-Cell Lymphoma |
title_short | The Metabolism and Immune Environment in Diffuse Large B-Cell Lymphoma |
title_sort | metabolism and immune environment in diffuse large b-cell lymphoma |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300995/ https://www.ncbi.nlm.nih.gov/pubmed/37367892 http://dx.doi.org/10.3390/metabo13060734 |
work_keys_str_mv | AT wujianbo themetabolismandimmuneenvironmentindiffuselargebcelllymphoma AT mengfuqing themetabolismandimmuneenvironmentindiffuselargebcelllymphoma AT randanyang themetabolismandimmuneenvironmentindiffuselargebcelllymphoma AT songyalong themetabolismandimmuneenvironmentindiffuselargebcelllymphoma AT dangyunkun themetabolismandimmuneenvironmentindiffuselargebcelllymphoma AT laifan themetabolismandimmuneenvironmentindiffuselargebcelllymphoma AT yanglongyan themetabolismandimmuneenvironmentindiffuselargebcelllymphoma AT dengmi themetabolismandimmuneenvironmentindiffuselargebcelllymphoma AT songyuqin themetabolismandimmuneenvironmentindiffuselargebcelllymphoma AT zhujun themetabolismandimmuneenvironmentindiffuselargebcelllymphoma AT wujianbo metabolismandimmuneenvironmentindiffuselargebcelllymphoma AT mengfuqing metabolismandimmuneenvironmentindiffuselargebcelllymphoma AT randanyang metabolismandimmuneenvironmentindiffuselargebcelllymphoma AT songyalong metabolismandimmuneenvironmentindiffuselargebcelllymphoma AT dangyunkun metabolismandimmuneenvironmentindiffuselargebcelllymphoma AT laifan metabolismandimmuneenvironmentindiffuselargebcelllymphoma AT yanglongyan metabolismandimmuneenvironmentindiffuselargebcelllymphoma AT dengmi metabolismandimmuneenvironmentindiffuselargebcelllymphoma AT songyuqin metabolismandimmuneenvironmentindiffuselargebcelllymphoma AT zhujun metabolismandimmuneenvironmentindiffuselargebcelllymphoma |