Vertebrate and Invertebrate Animal and New In Vitro Models for Studying Neisseria Biology

The history of Neisseria research has involved the use of a wide variety of vertebrate and invertebrate animal models, from insects to humans. In this review, we itemise these models and describe how they have made significant contributions to understanding the pathophysiology of Neisseria infection...

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Detalles Bibliográficos
Autores principales: Girgis, Michael M., Christodoulides, Myron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301118/
https://www.ncbi.nlm.nih.gov/pubmed/37375472
http://dx.doi.org/10.3390/pathogens12060782
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author Girgis, Michael M.
Christodoulides, Myron
author_facet Girgis, Michael M.
Christodoulides, Myron
author_sort Girgis, Michael M.
collection PubMed
description The history of Neisseria research has involved the use of a wide variety of vertebrate and invertebrate animal models, from insects to humans. In this review, we itemise these models and describe how they have made significant contributions to understanding the pathophysiology of Neisseria infections and to the development and testing of vaccines and antimicrobials. We also look ahead, briefly, to their potential replacement by complex in vitro cellular models.
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spelling pubmed-103011182023-06-29 Vertebrate and Invertebrate Animal and New In Vitro Models for Studying Neisseria Biology Girgis, Michael M. Christodoulides, Myron Pathogens Review The history of Neisseria research has involved the use of a wide variety of vertebrate and invertebrate animal models, from insects to humans. In this review, we itemise these models and describe how they have made significant contributions to understanding the pathophysiology of Neisseria infections and to the development and testing of vaccines and antimicrobials. We also look ahead, briefly, to their potential replacement by complex in vitro cellular models. MDPI 2023-05-30 /pmc/articles/PMC10301118/ /pubmed/37375472 http://dx.doi.org/10.3390/pathogens12060782 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Girgis, Michael M.
Christodoulides, Myron
Vertebrate and Invertebrate Animal and New In Vitro Models for Studying Neisseria Biology
title Vertebrate and Invertebrate Animal and New In Vitro Models for Studying Neisseria Biology
title_full Vertebrate and Invertebrate Animal and New In Vitro Models for Studying Neisseria Biology
title_fullStr Vertebrate and Invertebrate Animal and New In Vitro Models for Studying Neisseria Biology
title_full_unstemmed Vertebrate and Invertebrate Animal and New In Vitro Models for Studying Neisseria Biology
title_short Vertebrate and Invertebrate Animal and New In Vitro Models for Studying Neisseria Biology
title_sort vertebrate and invertebrate animal and new in vitro models for studying neisseria biology
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301118/
https://www.ncbi.nlm.nih.gov/pubmed/37375472
http://dx.doi.org/10.3390/pathogens12060782
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AT christodoulidesmyron vertebrateandinvertebrateanimalandnewinvitromodelsforstudyingneisseriabiology

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