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Optimization of Supercritical Fluid CO(2) Extraction from Yellow Horn Seed and Its Anti-Fatigue and Antioxidant Activity

A supercritical fluid carbon dioxide (SF-CO(2)) extraction method was used to obtain the optimum process for extracting yellow horn seed oil. The anti-fatigue and antioxidant properties of the extracted oil were investigated through animal experiments. The optimum process conditions for SF-CO(2) ext...

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Detalles Bibliográficos
Autores principales: Lyu, Siyan, Wang, Haoran, Ma, Tingjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301247/
https://www.ncbi.nlm.nih.gov/pubmed/37375407
http://dx.doi.org/10.3390/molecules28124853
Descripción
Sumario:A supercritical fluid carbon dioxide (SF-CO(2)) extraction method was used to obtain the optimum process for extracting yellow horn seed oil. The anti-fatigue and antioxidant properties of the extracted oil were investigated through animal experiments. The optimum process conditions for SF-CO(2) extraction of the yellow horn oil were 40 MPa, 50 °C and 120 min, with an extraction yield of 31.61%. The high-dose group of yellow horn oil could significantly increase the weight-bearing swimming time, the hepatic glycogen (HG) content and decrease the lactic acid (LA) content and blood urea nitrogen (BUN) content (p < 0.05) in mice. Moreover, it improved the antioxidant ability by reducing the malondialdehyde (MDA) content (p < 0.01) and raising the glutathione reductase (GR) content and superoxide dismutase (SOD) content (p < 0.05) in mice. Yellow horn oil has the effects of being an anti-fatigue and antioxidant substance, which provides a basis for its further utilization and development.