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Optimization of Supercritical Fluid CO(2) Extraction from Yellow Horn Seed and Its Anti-Fatigue and Antioxidant Activity
A supercritical fluid carbon dioxide (SF-CO(2)) extraction method was used to obtain the optimum process for extracting yellow horn seed oil. The anti-fatigue and antioxidant properties of the extracted oil were investigated through animal experiments. The optimum process conditions for SF-CO(2) ext...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301247/ https://www.ncbi.nlm.nih.gov/pubmed/37375407 http://dx.doi.org/10.3390/molecules28124853 |
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author | Lyu, Siyan Wang, Haoran Ma, Tingjun |
author_facet | Lyu, Siyan Wang, Haoran Ma, Tingjun |
author_sort | Lyu, Siyan |
collection | PubMed |
description | A supercritical fluid carbon dioxide (SF-CO(2)) extraction method was used to obtain the optimum process for extracting yellow horn seed oil. The anti-fatigue and antioxidant properties of the extracted oil were investigated through animal experiments. The optimum process conditions for SF-CO(2) extraction of the yellow horn oil were 40 MPa, 50 °C and 120 min, with an extraction yield of 31.61%. The high-dose group of yellow horn oil could significantly increase the weight-bearing swimming time, the hepatic glycogen (HG) content and decrease the lactic acid (LA) content and blood urea nitrogen (BUN) content (p < 0.05) in mice. Moreover, it improved the antioxidant ability by reducing the malondialdehyde (MDA) content (p < 0.01) and raising the glutathione reductase (GR) content and superoxide dismutase (SOD) content (p < 0.05) in mice. Yellow horn oil has the effects of being an anti-fatigue and antioxidant substance, which provides a basis for its further utilization and development. |
format | Online Article Text |
id | pubmed-10301247 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-103012472023-06-29 Optimization of Supercritical Fluid CO(2) Extraction from Yellow Horn Seed and Its Anti-Fatigue and Antioxidant Activity Lyu, Siyan Wang, Haoran Ma, Tingjun Molecules Article A supercritical fluid carbon dioxide (SF-CO(2)) extraction method was used to obtain the optimum process for extracting yellow horn seed oil. The anti-fatigue and antioxidant properties of the extracted oil were investigated through animal experiments. The optimum process conditions for SF-CO(2) extraction of the yellow horn oil were 40 MPa, 50 °C and 120 min, with an extraction yield of 31.61%. The high-dose group of yellow horn oil could significantly increase the weight-bearing swimming time, the hepatic glycogen (HG) content and decrease the lactic acid (LA) content and blood urea nitrogen (BUN) content (p < 0.05) in mice. Moreover, it improved the antioxidant ability by reducing the malondialdehyde (MDA) content (p < 0.01) and raising the glutathione reductase (GR) content and superoxide dismutase (SOD) content (p < 0.05) in mice. Yellow horn oil has the effects of being an anti-fatigue and antioxidant substance, which provides a basis for its further utilization and development. MDPI 2023-06-19 /pmc/articles/PMC10301247/ /pubmed/37375407 http://dx.doi.org/10.3390/molecules28124853 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Lyu, Siyan Wang, Haoran Ma, Tingjun Optimization of Supercritical Fluid CO(2) Extraction from Yellow Horn Seed and Its Anti-Fatigue and Antioxidant Activity |
title | Optimization of Supercritical Fluid CO(2) Extraction from Yellow Horn Seed and Its Anti-Fatigue and Antioxidant Activity |
title_full | Optimization of Supercritical Fluid CO(2) Extraction from Yellow Horn Seed and Its Anti-Fatigue and Antioxidant Activity |
title_fullStr | Optimization of Supercritical Fluid CO(2) Extraction from Yellow Horn Seed and Its Anti-Fatigue and Antioxidant Activity |
title_full_unstemmed | Optimization of Supercritical Fluid CO(2) Extraction from Yellow Horn Seed and Its Anti-Fatigue and Antioxidant Activity |
title_short | Optimization of Supercritical Fluid CO(2) Extraction from Yellow Horn Seed and Its Anti-Fatigue and Antioxidant Activity |
title_sort | optimization of supercritical fluid co(2) extraction from yellow horn seed and its anti-fatigue and antioxidant activity |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301247/ https://www.ncbi.nlm.nih.gov/pubmed/37375407 http://dx.doi.org/10.3390/molecules28124853 |
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