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The Female Reproductive Tract Microbiota: Friends and Foe
We do not seem to be the only owner of our body; it houses a large population of microorganisms. Through countless years of coevolution, microbes and hosts have developed complex relationships. In the past few years, the impact of microbial communities on their host has received significant attentio...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301250/ https://www.ncbi.nlm.nih.gov/pubmed/37374096 http://dx.doi.org/10.3390/life13061313 |
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author | Kumar, Lokesh Dwivedi, Monika Jain, Natasha Shete, Pranali Solanki, Subhash Gupta, Rahul Jain, Ashish |
author_facet | Kumar, Lokesh Dwivedi, Monika Jain, Natasha Shete, Pranali Solanki, Subhash Gupta, Rahul Jain, Ashish |
author_sort | Kumar, Lokesh |
collection | PubMed |
description | We do not seem to be the only owner of our body; it houses a large population of microorganisms. Through countless years of coevolution, microbes and hosts have developed complex relationships. In the past few years, the impact of microbial communities on their host has received significant attention. Advanced molecular sequencing techniques have revealed a remarkable diversity of the organ-specific microbiota populations, including in the reproductive tract. Currently, the goal of researchers has shifted to generate and perceive the molecular data of those hidden travelers of our body and harness them for the betterment of human health. Recently, microbial communities of the lower and upper reproductive tract and their correlation with the implication in reproductive health and disease have been extensively studied. Many intrinsic and extrinsic factors influences the female reproductive tract microbiota (FRTM) that directly affects the reproductive health. It is now believed that FRTM dominated by Lactobacilli may play an essential role in obstetric health beyond the woman’s intimate comfort and well-being. Women with altered microbiota may face numerous health-related issues. Altered microbiota can be manipulated and restored to their original shape to re-establish normal reproductive health. The aim of the present review is to summarize the FRTM functional aspects that influence reproductive health. |
format | Online Article Text |
id | pubmed-10301250 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-103012502023-06-29 The Female Reproductive Tract Microbiota: Friends and Foe Kumar, Lokesh Dwivedi, Monika Jain, Natasha Shete, Pranali Solanki, Subhash Gupta, Rahul Jain, Ashish Life (Basel) Review We do not seem to be the only owner of our body; it houses a large population of microorganisms. Through countless years of coevolution, microbes and hosts have developed complex relationships. In the past few years, the impact of microbial communities on their host has received significant attention. Advanced molecular sequencing techniques have revealed a remarkable diversity of the organ-specific microbiota populations, including in the reproductive tract. Currently, the goal of researchers has shifted to generate and perceive the molecular data of those hidden travelers of our body and harness them for the betterment of human health. Recently, microbial communities of the lower and upper reproductive tract and their correlation with the implication in reproductive health and disease have been extensively studied. Many intrinsic and extrinsic factors influences the female reproductive tract microbiota (FRTM) that directly affects the reproductive health. It is now believed that FRTM dominated by Lactobacilli may play an essential role in obstetric health beyond the woman’s intimate comfort and well-being. Women with altered microbiota may face numerous health-related issues. Altered microbiota can be manipulated and restored to their original shape to re-establish normal reproductive health. The aim of the present review is to summarize the FRTM functional aspects that influence reproductive health. MDPI 2023-06-01 /pmc/articles/PMC10301250/ /pubmed/37374096 http://dx.doi.org/10.3390/life13061313 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Kumar, Lokesh Dwivedi, Monika Jain, Natasha Shete, Pranali Solanki, Subhash Gupta, Rahul Jain, Ashish The Female Reproductive Tract Microbiota: Friends and Foe |
title | The Female Reproductive Tract Microbiota: Friends and Foe |
title_full | The Female Reproductive Tract Microbiota: Friends and Foe |
title_fullStr | The Female Reproductive Tract Microbiota: Friends and Foe |
title_full_unstemmed | The Female Reproductive Tract Microbiota: Friends and Foe |
title_short | The Female Reproductive Tract Microbiota: Friends and Foe |
title_sort | female reproductive tract microbiota: friends and foe |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301250/ https://www.ncbi.nlm.nih.gov/pubmed/37374096 http://dx.doi.org/10.3390/life13061313 |
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