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The Female Reproductive Tract Microbiota: Friends and Foe

We do not seem to be the only owner of our body; it houses a large population of microorganisms. Through countless years of coevolution, microbes and hosts have developed complex relationships. In the past few years, the impact of microbial communities on their host has received significant attentio...

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Autores principales: Kumar, Lokesh, Dwivedi, Monika, Jain, Natasha, Shete, Pranali, Solanki, Subhash, Gupta, Rahul, Jain, Ashish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301250/
https://www.ncbi.nlm.nih.gov/pubmed/37374096
http://dx.doi.org/10.3390/life13061313
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author Kumar, Lokesh
Dwivedi, Monika
Jain, Natasha
Shete, Pranali
Solanki, Subhash
Gupta, Rahul
Jain, Ashish
author_facet Kumar, Lokesh
Dwivedi, Monika
Jain, Natasha
Shete, Pranali
Solanki, Subhash
Gupta, Rahul
Jain, Ashish
author_sort Kumar, Lokesh
collection PubMed
description We do not seem to be the only owner of our body; it houses a large population of microorganisms. Through countless years of coevolution, microbes and hosts have developed complex relationships. In the past few years, the impact of microbial communities on their host has received significant attention. Advanced molecular sequencing techniques have revealed a remarkable diversity of the organ-specific microbiota populations, including in the reproductive tract. Currently, the goal of researchers has shifted to generate and perceive the molecular data of those hidden travelers of our body and harness them for the betterment of human health. Recently, microbial communities of the lower and upper reproductive tract and their correlation with the implication in reproductive health and disease have been extensively studied. Many intrinsic and extrinsic factors influences the female reproductive tract microbiota (FRTM) that directly affects the reproductive health. It is now believed that FRTM dominated by Lactobacilli may play an essential role in obstetric health beyond the woman’s intimate comfort and well-being. Women with altered microbiota may face numerous health-related issues. Altered microbiota can be manipulated and restored to their original shape to re-establish normal reproductive health. The aim of the present review is to summarize the FRTM functional aspects that influence reproductive health.
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spelling pubmed-103012502023-06-29 The Female Reproductive Tract Microbiota: Friends and Foe Kumar, Lokesh Dwivedi, Monika Jain, Natasha Shete, Pranali Solanki, Subhash Gupta, Rahul Jain, Ashish Life (Basel) Review We do not seem to be the only owner of our body; it houses a large population of microorganisms. Through countless years of coevolution, microbes and hosts have developed complex relationships. In the past few years, the impact of microbial communities on their host has received significant attention. Advanced molecular sequencing techniques have revealed a remarkable diversity of the organ-specific microbiota populations, including in the reproductive tract. Currently, the goal of researchers has shifted to generate and perceive the molecular data of those hidden travelers of our body and harness them for the betterment of human health. Recently, microbial communities of the lower and upper reproductive tract and their correlation with the implication in reproductive health and disease have been extensively studied. Many intrinsic and extrinsic factors influences the female reproductive tract microbiota (FRTM) that directly affects the reproductive health. It is now believed that FRTM dominated by Lactobacilli may play an essential role in obstetric health beyond the woman’s intimate comfort and well-being. Women with altered microbiota may face numerous health-related issues. Altered microbiota can be manipulated and restored to their original shape to re-establish normal reproductive health. The aim of the present review is to summarize the FRTM functional aspects that influence reproductive health. MDPI 2023-06-01 /pmc/articles/PMC10301250/ /pubmed/37374096 http://dx.doi.org/10.3390/life13061313 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Kumar, Lokesh
Dwivedi, Monika
Jain, Natasha
Shete, Pranali
Solanki, Subhash
Gupta, Rahul
Jain, Ashish
The Female Reproductive Tract Microbiota: Friends and Foe
title The Female Reproductive Tract Microbiota: Friends and Foe
title_full The Female Reproductive Tract Microbiota: Friends and Foe
title_fullStr The Female Reproductive Tract Microbiota: Friends and Foe
title_full_unstemmed The Female Reproductive Tract Microbiota: Friends and Foe
title_short The Female Reproductive Tract Microbiota: Friends and Foe
title_sort female reproductive tract microbiota: friends and foe
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301250/
https://www.ncbi.nlm.nih.gov/pubmed/37374096
http://dx.doi.org/10.3390/life13061313
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