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Virtual Screening of a Marine Natural Product Database for In Silico Identification of a Potential Acetylcholinesterase Inhibitor

Alzheimer’s disease is characterized by amyloid-beta aggregation and neurofibrillary tangles. Acetylcholinesterase (AChE) hydrolyses acetylcholine and induces amyloid-beta aggregation. Acetylcholinesterase inhibitors (AChEI) inhibit this aggregation by binding to AChE, making it a potential target f...

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Detalles Bibliográficos
Autores principales:	Gade, Anushree Chandrashekhar, Murahari, Manikanta, Pavadai, Parasuraman, Kumar, Maushmi Shailesh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301296/ https://www.ncbi.nlm.nih.gov/pubmed/37374081 http://dx.doi.org/10.3390/life13061298

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