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Maternal Nutritional Status and the Microbiome across the Pregnancy and the Post-Partum Period

Appropriate nutrition during pregnancy and the post-partum period is vital for both the mothers and their offspring. Both under- and over-nourished status may have important microbial implications on the maternal and infant gut microbiomes. Alterations in the microbiome can have implications for a p...

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Autores principales: Strobel, Katie M., Juul, Sandra E., Hendrixson, David Taylor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301339/
https://www.ncbi.nlm.nih.gov/pubmed/37375071
http://dx.doi.org/10.3390/microorganisms11061569
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author Strobel, Katie M.
Juul, Sandra E.
Hendrixson, David Taylor
author_facet Strobel, Katie M.
Juul, Sandra E.
Hendrixson, David Taylor
author_sort Strobel, Katie M.
collection PubMed
description Appropriate nutrition during pregnancy and the post-partum period is vital for both the mothers and their offspring. Both under- and over-nourished status may have important microbial implications on the maternal and infant gut microbiomes. Alterations in the microbiome can have implications for a person’s risk of obesity and metabolic diseases. In this review, we examine alterations in the maternal gut, vaginal, placental, and milk microbiomes in the context of pre-pregnancy BMI, gestational weight gain, body composition, gestational diabetes, and maternal diet. We also investigate how the infant gut microbiome may be altered by these different parameters. Many of the microbial changes seen in under- and over-nourished states in birthing parents may result in long-term implications for the health of offspring. Differences in diet appear to be a major driver of the maternal and subsequently milk and offspring microbiomes. Further prospective longitudinal cohort studies are needed to examine nutrition and the microbiome to better understand its implications. Additionally, trials involving dietary interventions in child-bearing age adults should be explored to improve the mother and child’s risks for metabolic diseases.
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spelling pubmed-103013392023-06-29 Maternal Nutritional Status and the Microbiome across the Pregnancy and the Post-Partum Period Strobel, Katie M. Juul, Sandra E. Hendrixson, David Taylor Microorganisms Review Appropriate nutrition during pregnancy and the post-partum period is vital for both the mothers and their offspring. Both under- and over-nourished status may have important microbial implications on the maternal and infant gut microbiomes. Alterations in the microbiome can have implications for a person’s risk of obesity and metabolic diseases. In this review, we examine alterations in the maternal gut, vaginal, placental, and milk microbiomes in the context of pre-pregnancy BMI, gestational weight gain, body composition, gestational diabetes, and maternal diet. We also investigate how the infant gut microbiome may be altered by these different parameters. Many of the microbial changes seen in under- and over-nourished states in birthing parents may result in long-term implications for the health of offspring. Differences in diet appear to be a major driver of the maternal and subsequently milk and offspring microbiomes. Further prospective longitudinal cohort studies are needed to examine nutrition and the microbiome to better understand its implications. Additionally, trials involving dietary interventions in child-bearing age adults should be explored to improve the mother and child’s risks for metabolic diseases. MDPI 2023-06-13 /pmc/articles/PMC10301339/ /pubmed/37375071 http://dx.doi.org/10.3390/microorganisms11061569 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Strobel, Katie M.
Juul, Sandra E.
Hendrixson, David Taylor
Maternal Nutritional Status and the Microbiome across the Pregnancy and the Post-Partum Period
title Maternal Nutritional Status and the Microbiome across the Pregnancy and the Post-Partum Period
title_full Maternal Nutritional Status and the Microbiome across the Pregnancy and the Post-Partum Period
title_fullStr Maternal Nutritional Status and the Microbiome across the Pregnancy and the Post-Partum Period
title_full_unstemmed Maternal Nutritional Status and the Microbiome across the Pregnancy and the Post-Partum Period
title_short Maternal Nutritional Status and the Microbiome across the Pregnancy and the Post-Partum Period
title_sort maternal nutritional status and the microbiome across the pregnancy and the post-partum period
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301339/
https://www.ncbi.nlm.nih.gov/pubmed/37375071
http://dx.doi.org/10.3390/microorganisms11061569
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