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Diagnosis of Left-Sided Mechanical Prosthetic Valve Thrombosis: A Pictorial Review
Although transcatheter valve therapy is rapidly evolving, surgical valve replacement is still required in many patients with severe left-side valve stenosis or regurgitation, the mechanical bi-leaflet heart valve being the standard prosthesis type in younger patients. Moreover, the prevalence of val...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301355/ https://www.ncbi.nlm.nih.gov/pubmed/37373956 http://dx.doi.org/10.3390/jpm13060967 |
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author | Serban, Adela Dadarlat-Pop, Alexandra Achim, Alexandru Gavan, Dana Pepine, Diana Rancea, Raluca Tomoaia, Raluca |
author_facet | Serban, Adela Dadarlat-Pop, Alexandra Achim, Alexandru Gavan, Dana Pepine, Diana Rancea, Raluca Tomoaia, Raluca |
author_sort | Serban, Adela |
collection | PubMed |
description | Although transcatheter valve therapy is rapidly evolving, surgical valve replacement is still required in many patients with severe left-side valve stenosis or regurgitation, the mechanical bi-leaflet heart valve being the standard prosthesis type in younger patients. Moreover, the prevalence of valvular heart disease is steadily increasing, especially in industrialized countries, and the problem of lifelong efficient anticoagulation of these patients remains fundamental, especially in the context where vitamin K antagonists continue to be the current standard of anticoagulation despite a level of oscillating anticoagulation. In this setting, avoiding prosthetic valve thrombosis after surgery is the number one objective for both the patient and the responsible physicians. Although rare, this complication is life threatening, with the sudden onset of acute cardiac failure such as acute pulmonary edema, cardiogenic shock, or sudden cardiac death and inadequate anticoagulation remaining the leading cause of prosthesis thrombosis, along with other risk factors. The availability of multimodal imaging techniques enables and encompasses to a full extent the diagnosis of mechanical valve thrombosis. The gold-standard diagnostic methods are transthoracic and transesophageal echocardiography. Moreover, 3D ultrasound has undoubted value in giving a more accurate description of the thrombus’s extension. When transthoracic and transesophageal echocardiography are uncertain, the multidetector computer tomography examination is an important complementary imaging method. Fluoroscopy is also an excellent tool for evaluating the mobility of prosthetic discs. Each method complements the other to differentiate an acute mechanical valve thrombosis from other prosthetic valve pathologies such as pannus formation or infective endocarditis and aids the physician in accurately establishing the treatment method (surgical or pharmaceutical) and its optimal timing. The aim of this pictorial review was to discuss from an imagistic perspective the mechanical prosthetic aortic and mitral valve thrombosis and to provide an overview of the essential role of non-invasive exploration in the treatment of this severe complication. |
format | Online Article Text |
id | pubmed-10301355 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-103013552023-06-29 Diagnosis of Left-Sided Mechanical Prosthetic Valve Thrombosis: A Pictorial Review Serban, Adela Dadarlat-Pop, Alexandra Achim, Alexandru Gavan, Dana Pepine, Diana Rancea, Raluca Tomoaia, Raluca J Pers Med Review Although transcatheter valve therapy is rapidly evolving, surgical valve replacement is still required in many patients with severe left-side valve stenosis or regurgitation, the mechanical bi-leaflet heart valve being the standard prosthesis type in younger patients. Moreover, the prevalence of valvular heart disease is steadily increasing, especially in industrialized countries, and the problem of lifelong efficient anticoagulation of these patients remains fundamental, especially in the context where vitamin K antagonists continue to be the current standard of anticoagulation despite a level of oscillating anticoagulation. In this setting, avoiding prosthetic valve thrombosis after surgery is the number one objective for both the patient and the responsible physicians. Although rare, this complication is life threatening, with the sudden onset of acute cardiac failure such as acute pulmonary edema, cardiogenic shock, or sudden cardiac death and inadequate anticoagulation remaining the leading cause of prosthesis thrombosis, along with other risk factors. The availability of multimodal imaging techniques enables and encompasses to a full extent the diagnosis of mechanical valve thrombosis. The gold-standard diagnostic methods are transthoracic and transesophageal echocardiography. Moreover, 3D ultrasound has undoubted value in giving a more accurate description of the thrombus’s extension. When transthoracic and transesophageal echocardiography are uncertain, the multidetector computer tomography examination is an important complementary imaging method. Fluoroscopy is also an excellent tool for evaluating the mobility of prosthetic discs. Each method complements the other to differentiate an acute mechanical valve thrombosis from other prosthetic valve pathologies such as pannus formation or infective endocarditis and aids the physician in accurately establishing the treatment method (surgical or pharmaceutical) and its optimal timing. The aim of this pictorial review was to discuss from an imagistic perspective the mechanical prosthetic aortic and mitral valve thrombosis and to provide an overview of the essential role of non-invasive exploration in the treatment of this severe complication. MDPI 2023-06-08 /pmc/articles/PMC10301355/ /pubmed/37373956 http://dx.doi.org/10.3390/jpm13060967 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Serban, Adela Dadarlat-Pop, Alexandra Achim, Alexandru Gavan, Dana Pepine, Diana Rancea, Raluca Tomoaia, Raluca Diagnosis of Left-Sided Mechanical Prosthetic Valve Thrombosis: A Pictorial Review |
title | Diagnosis of Left-Sided Mechanical Prosthetic Valve Thrombosis: A Pictorial Review |
title_full | Diagnosis of Left-Sided Mechanical Prosthetic Valve Thrombosis: A Pictorial Review |
title_fullStr | Diagnosis of Left-Sided Mechanical Prosthetic Valve Thrombosis: A Pictorial Review |
title_full_unstemmed | Diagnosis of Left-Sided Mechanical Prosthetic Valve Thrombosis: A Pictorial Review |
title_short | Diagnosis of Left-Sided Mechanical Prosthetic Valve Thrombosis: A Pictorial Review |
title_sort | diagnosis of left-sided mechanical prosthetic valve thrombosis: a pictorial review |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301355/ https://www.ncbi.nlm.nih.gov/pubmed/37373956 http://dx.doi.org/10.3390/jpm13060967 |
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