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Recent Advances in Doxorubicin Formulation to Enhance Pharmacokinetics and Tumor Targeting

Doxorubicin (DOX), a widely used drug in cancer chemotherapy, induces cell death via multiple intracellular interactions, generating reactive oxygen species and DNA-adducted configurations that induce apoptosis, topoisomerase II inhibition, and histone eviction. Despite its wide therapeutic efficacy...

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Detalles Bibliográficos
Autores principales:	Lee, Jihoon, Choi, Min-Koo, Song, Im-Sook
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301446/ https://www.ncbi.nlm.nih.gov/pubmed/37375753 http://dx.doi.org/10.3390/ph16060802

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