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Fe-Based Metal Organic Frameworks (Fe-MOFs) for Bio-Related Applications

Metal–organic frameworks (MOFs) are porous materials composed of metal ions and organic ligands. Due to their large surface area, easy modification, and good biocompatibility, MOFs are often used in bio-related fields. Fe-based metal–organic frameworks (Fe-MOFs), as important types of MOF, are favor...

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Autores principales: Zhu, Rongyue, Cai, Mengru, Fu, Tingting, Yin, Dongge, Peng, Hulinyue, Liao, Shilang, Du, Yuji, Kong, Jiahui, Ni, Jian, Yin, Xingbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301457/
https://www.ncbi.nlm.nih.gov/pubmed/37376050
http://dx.doi.org/10.3390/pharmaceutics15061599
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author Zhu, Rongyue
Cai, Mengru
Fu, Tingting
Yin, Dongge
Peng, Hulinyue
Liao, Shilang
Du, Yuji
Kong, Jiahui
Ni, Jian
Yin, Xingbin
author_facet Zhu, Rongyue
Cai, Mengru
Fu, Tingting
Yin, Dongge
Peng, Hulinyue
Liao, Shilang
Du, Yuji
Kong, Jiahui
Ni, Jian
Yin, Xingbin
author_sort Zhu, Rongyue
collection PubMed
description Metal–organic frameworks (MOFs) are porous materials composed of metal ions and organic ligands. Due to their large surface area, easy modification, and good biocompatibility, MOFs are often used in bio-related fields. Fe-based metal–organic frameworks (Fe-MOFs), as important types of MOF, are favored by biomedical researchers for their advantages, such as low toxicity, good stability, high drug-loading capacity, and flexible structure. Fe-MOFs are diverse and widely used. Many new Fe-MOFs have appeared in recent years, with new modification methods and innovative design ideas, leading to the transformation of Fe-MOFs from single-mode therapy to multi-mode therapy. In this paper, the therapeutic principles, classification, characteristics, preparation methods, surface modification, and applications of Fe-MOFs in recent years are reviewed to understand the development trends and existing problems in Fe-MOFs, with the view to provide new ideas and directions for future research.
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spelling pubmed-103014572023-06-29 Fe-Based Metal Organic Frameworks (Fe-MOFs) for Bio-Related Applications Zhu, Rongyue Cai, Mengru Fu, Tingting Yin, Dongge Peng, Hulinyue Liao, Shilang Du, Yuji Kong, Jiahui Ni, Jian Yin, Xingbin Pharmaceutics Review Metal–organic frameworks (MOFs) are porous materials composed of metal ions and organic ligands. Due to their large surface area, easy modification, and good biocompatibility, MOFs are often used in bio-related fields. Fe-based metal–organic frameworks (Fe-MOFs), as important types of MOF, are favored by biomedical researchers for their advantages, such as low toxicity, good stability, high drug-loading capacity, and flexible structure. Fe-MOFs are diverse and widely used. Many new Fe-MOFs have appeared in recent years, with new modification methods and innovative design ideas, leading to the transformation of Fe-MOFs from single-mode therapy to multi-mode therapy. In this paper, the therapeutic principles, classification, characteristics, preparation methods, surface modification, and applications of Fe-MOFs in recent years are reviewed to understand the development trends and existing problems in Fe-MOFs, with the view to provide new ideas and directions for future research. MDPI 2023-05-26 /pmc/articles/PMC10301457/ /pubmed/37376050 http://dx.doi.org/10.3390/pharmaceutics15061599 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Zhu, Rongyue
Cai, Mengru
Fu, Tingting
Yin, Dongge
Peng, Hulinyue
Liao, Shilang
Du, Yuji
Kong, Jiahui
Ni, Jian
Yin, Xingbin
Fe-Based Metal Organic Frameworks (Fe-MOFs) for Bio-Related Applications
title Fe-Based Metal Organic Frameworks (Fe-MOFs) for Bio-Related Applications
title_full Fe-Based Metal Organic Frameworks (Fe-MOFs) for Bio-Related Applications
title_fullStr Fe-Based Metal Organic Frameworks (Fe-MOFs) for Bio-Related Applications
title_full_unstemmed Fe-Based Metal Organic Frameworks (Fe-MOFs) for Bio-Related Applications
title_short Fe-Based Metal Organic Frameworks (Fe-MOFs) for Bio-Related Applications
title_sort fe-based metal organic frameworks (fe-mofs) for bio-related applications
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301457/
https://www.ncbi.nlm.nih.gov/pubmed/37376050
http://dx.doi.org/10.3390/pharmaceutics15061599
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