Determination of the Duplicated CYP2D6 Allele Using Real-Time PCR Signal: An Alternative Approach

CYP2D6 duplication has important pharmacogenomic implications. Reflex testing with long-range PCR (LR-PCR) can resolve the genotype when a duplication and alleles with differing activity scores are detected. We evaluated whether visual inspection of plots from real-time-PCR-based targeted genotyping...

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Detalles Bibliográficos
Autores principales: Atiq, Mazen A., Peterson, Sandra E., Langman, Loralie J., Baudhuin, Linnea M., Black, John L., Moyer, Ann M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301474/
https://www.ncbi.nlm.nih.gov/pubmed/37373874
http://dx.doi.org/10.3390/jpm13060883

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301474/
https://www.ncbi.nlm.nih.gov/pubmed/37373874
http://dx.doi.org/10.3390/jpm13060883

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