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Determination of the Duplicated CYP2D6 Allele Using Real-Time PCR Signal: An Alternative Approach
CYP2D6 duplication has important pharmacogenomic implications. Reflex testing with long-range PCR (LR-PCR) can resolve the genotype when a duplication and alleles with differing activity scores are detected. We evaluated whether visual inspection of plots from real-time-PCR-based targeted genotyping...
Autores principales: | Atiq, Mazen A., Peterson, Sandra E., Langman, Loralie J., Baudhuin, Linnea M., Black, John L., Moyer, Ann M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301474/ https://www.ncbi.nlm.nih.gov/pubmed/37373874 http://dx.doi.org/10.3390/jpm13060883 |
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