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Synthesis, Crystal Structure, DFT, and Anticancer Activity of Some Imine-Type Compounds via Routine Schiff Base Reaction: An Example of Unexpected Cyclization to Oxazine Derivative

The synthesis, characterization, and anticancer properties of three imine-type compounds 1–3 and an unexpected oxazine derivative 4 are presented. The reaction of p-dimethylaminobenzaldehyde or m-nitrobenzaldehyde with hydroxylamine hydrochloride afforded the corresponding oximes 1–2 in good yields....

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Detalles Bibliográficos
Autores principales: Lasri, Jamal, Eltayeb, Naser E., Soliman, Saied M., Ali, Ehab M. M., Alhayyani, Sultan, Akhdhar, Abdullah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301602/
https://www.ncbi.nlm.nih.gov/pubmed/37375321
http://dx.doi.org/10.3390/molecules28124766