Cargando…

ASF Vaccine Candidate ASFV-G-∆I177L Does Not Exhibit Residual Virulence in Long-Term Clinical Studies

African swine fever (ASF) is an important disease in swine currently producing a pandemic affecting pig production worldwide. Except in Vietnam, where two vaccines were recently approved for controlled use in the field, no vaccine is commercially available for disease control. Up to now, the most ef...

Descripción completa

Detalles Bibliográficos
Autores principales:	Borca, Manuel V., Ramirez-Medina, Elizabeth, Silva, Ediane, Rai, Ayushi, Espinoza, Nallely, Velazquez-Salinas, Lauro, Gladue, Douglas P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301618/ https://www.ncbi.nlm.nih.gov/pubmed/37375495 http://dx.doi.org/10.3390/pathogens12060805

Ejemplares similares

Evaluation of the Function of the ASFV KP177R Gene, Encoding for Structural Protein p22, in the Process of Virus Replication and in Swine Virulence
por: Vuono, Elizabeth A., et al.
Publicado: (2021)

ASFV-G-∆I177L as an Effective Oral Nasal Vaccine against the Eurasia Strain of Africa Swine Fever
por: Borca, Manuel V., et al.
Publicado: (2021)

ASFV Gene A151R Is Involved in the Process of Virulence in Domestic Swine
por: Ramirez-Medina, Elizabeth, et al.
Publicado: (2022)

African Swine Fever Vaccine Candidate ASFV-G-ΔI177L Produced in the Swine Macrophage-Derived Cell Line IPKM Remains Genetically Stable and Protective against Homologous Virulent Challenge
por: Borca, Manuel V., et al.
Publicado: (2023)

Deletion of the ASFV dUTPase Gene E165R from the Genome of Highly Virulent African Swine Fever Virus Georgia 2010 Does Not Affect Virus Replication or Virulence in Domestic Pigs
por: Vuono, Elizabeth A., et al.
Publicado: (2022)

Evaluation of an ASFV RNA Helicase Gene A859L for Virus Replication and Swine Virulence
por: Ramirez-Medina, Elizabeth, et al.
Publicado: (2021)

Evaluation of the Function of ASFV Gene E66L in the Process of Virus Replication and Virulence in Swine
por: Ramirez-Medina, Elizabeth, et al.
Publicado: (2023)

The Presence of Virus Neutralizing Antibodies Is Highly Associated with Protection against Virulent Challenge in Domestic Pigs Immunized with ASFV live Attenuated Vaccine Candidates
por: Silva, Ediane B., et al.
Publicado: (2022)

Deletion of the H240R Gene in African Swine Fever Virus Partially Reduces Virus Virulence in Swine
por: Ramirez-Medina, Elizabeth, et al.
Publicado: (2023)

Evaluation of the Safety Profile of the ASFV Vaccine Candidate ASFV-G-ΔI177L
por: Tran, Xuan Hanh, et al.
Publicado: (2022)

Deletion of the EP296R Gene from the Genome of Highly Virulent African Swine Fever Virus Georgia 2010 Does Not Affect Virus Replication or Virulence in Domestic Pigs
por: Vuono, Elizabeth A., et al.
Publicado: (2022)

Deletion of an African Swine Fever Virus ATP-Dependent RNA Helicase QP509L from the Highly Virulent Georgia 2010 Strain Does Not Affect Replication or Virulence
por: Ramirez-Medina, Elizabeth, et al.
Publicado: (2022)

Deletion of African Swine Fever Virus Histone-like Protein, A104R from the Georgia Isolate Drastically Reduces Virus Virulence in Domestic Pigs
por: Ramirez-Medina, Elizabeth, et al.
Publicado: (2022)

Evaluation in Swine of a Recombinant Georgia 2010 African Swine Fever Virus Lacking the I8L Gene
por: Vuono, Elizabeth, et al.
Publicado: (2020)

Development and In Vivo Evaluation of a MGF110-1L Deletion Mutant in African Swine Fever Strain Georgia
por: Ramirez-Medina, Elizabeth, et al.
Publicado: (2021)

X69R Is a Non-Essential Gene That, When Deleted from African Swine Fever, Does Not Affect Virulence in Swine
por: Ramirez-Medina, Elizabeth, et al.
Publicado: (2020)

The C962R ORF of African Swine Fever Strain Georgia Is Non-Essential and Not Required for Virulence in Swine
por: Ramirez-Medina, Elizabeth., et al.
Publicado: (2020)

Development Real-Time PCR Assays to Genetically Differentiate Vaccinated Pigs From Infected Pigs With the Eurasian Strain of African Swine Fever Virus
por: Velazquez-Salinas, Lauro, et al.
Publicado: (2021)

Recombinant ASF Live Attenuated Virus Strains as Experimental Vaccine Candidates
por: Gladue, Douglas P., et al.
Publicado: (2022)

SERTA Domain Containing Protein 1 (SERTAD1) Interacts with Classical Swine Fever Virus Structural Glycoprotein E2, Which Is Involved in Virus Virulence in Swine
por: Vuono, Elizabeth A., et al.
Publicado: (2020)

Classical Swine Fever Virus Structural Glycoprotein E2 Interacts with Host Protein ACADM during the Virus Infectious Cycle
por: Vuono, Elizabeth, et al.
Publicado: (2023)

Evaluation of the Deletion of the African Swine Fever Virus Gene O174L from the Genome of the Georgia Isolate
por: Ramirez-Medina, Elizabeth, et al.
Publicado: (2023)

Evaluation in Swine of a Recombinant African Swine Fever Virus Lacking the MGF-360-1L Gene
por: Ramirez-Medina, Elizabeth, et al.
Publicado: (2020)

Identification of a Continuously Stable and Commercially Available Cell Line for the Identification of Infectious African Swine Fever Virus in Clinical Samples
por: Rai, Ayushi, et al.
Publicado: (2020)

Swine Host Protein Coiled-Coil Domain-Containing 115 (CCDC115) Interacts with Classical Swine Fever Virus Structural Glycoprotein E2 during Virus Replication
por: Vuono, Elizabeth A., et al.
Publicado: (2020)

Deletion of CD2-Like (CD2v) and C-Type Lectin-Like (EP153R) Genes from African Swine Fever Virus Georgia-∆9GL Abrogates Its Effectiveness as an Experimental Vaccine
por: Gladue, Douglas P., et al.
Publicado: (2020)

Deletion of CD2-like gene from the genome of African swine fever virus strain Georgia does not attenuate virulence in swine
por: Borca, Manuel V., et al.
Publicado: (2020)

The MGF360-16R ORF of African Swine Fever Virus Strain Georgia Encodes for a Nonessential Gene That Interacts with Host Proteins SERTAD3 and SDCBP
por: Ramírez-Medina, Elizabeth, et al.
Publicado: (2020)

Differential Effect of the Deletion of African Swine Fever Virus Virulence-Associated Genes in the Induction of Attenuation of the Highly Virulent Georgia Strain
por: Ramirez-Medina, Elizabeth, et al.
Publicado: (2019)

Experimental Infection of Domestic Pigs with an African Swine Fever Virus Field Strain Isolated in 2021 from the Dominican Republic
por: Ramirez-Medina, Elizabeth, et al.
Publicado: (2022)

Complete Structural Predictions of the Proteome of African Swine Fever Virus Strain Georgia 2007
por: Spinard, Edward, et al.
Publicado: (2022)

Optimization in the expression of ASFV proteins for the development of subunit vaccines using poxviruses as delivery vectors
por: Lopera-Madrid, Jaime, et al.
Publicado: (2021)

A Triple Gene-Deleted Pseudorabies Virus-Vectored Subunit PCV2b and CSFV Vaccine Protect Pigs against a Virulent CSFV Challenge
por: Silva, Ediane, et al.
Publicado: (2023)

Full genome sequence for the African swine fever virus outbreak in the Dominican Republic in 1980
por: Spinard, Edward, et al.
Publicado: (2023)

Development of a fluorescent ASFV strain that retains the ability to cause disease in swine
por: Borca, Manuel V., et al.
Publicado: (2017)

Positive Selection of ORF1ab, ORF3a, and ORF8 Genes Drives the Early Evolutionary Trends of SARS-CoV-2 During the 2020 COVID-19 Pandemic
por: Velazquez-Salinas, Lauro, et al.
Publicado: (2020)

Assessment of African swine fever vaccine candidate ASFV-G-∆MGF in a reversion to virulence study
por: Deutschmann, Paul, et al.
Publicado: (2023)

Deletion Mutants of the Attenuated Recombinant ASF Virus, BA71ΔCD2, Show Decreased Vaccine Efficacy
por: Lopez, Elisabeth, et al.
Publicado: (2021)

A Highly Effective African Swine Fever Virus Vaccine Elicits a Memory T Cell Response in Vaccinated Swine
por: Attreed, Sarah E., et al.
Publicado: (2022)

The 2022 Outbreaks of African Swine Fever Virus Demonstrate the First Report of Genotype II in Ghana
por: Spinard, Edward, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_gdp39bvnfo2q32v1evk6l0peqg