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Streptomyces and their specialised metabolites for phytopathogen control – comparative in vitro and in planta metabolic approaches

In the search for new crop protection microbial biocontrol agents, isolates from the genus Streptomyces are commonly found with promising attributes. Streptomyces are natural soil dwellers and have evolved as plant symbionts producing specialised metabolites with antibiotic and antifungal activities...

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Autores principales: Dow, Lachlan, Gallart, Marta, Ramarajan, Margaret, Law, Simon R., Thatcher, Louise F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301723/
https://www.ncbi.nlm.nih.gov/pubmed/37389291
http://dx.doi.org/10.3389/fpls.2023.1151912
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author Dow, Lachlan
Gallart, Marta
Ramarajan, Margaret
Law, Simon R.
Thatcher, Louise F.
author_facet Dow, Lachlan
Gallart, Marta
Ramarajan, Margaret
Law, Simon R.
Thatcher, Louise F.
author_sort Dow, Lachlan
collection PubMed
description In the search for new crop protection microbial biocontrol agents, isolates from the genus Streptomyces are commonly found with promising attributes. Streptomyces are natural soil dwellers and have evolved as plant symbionts producing specialised metabolites with antibiotic and antifungal activities. Streptomyces biocontrol strains can effectively suppress plant pathogens via direct antimicrobial activity, but also induce plant resistance through indirect biosynthetic pathways. The investigation of factors stimulating the production and release of Streptomyces bioactive compounds is commonly conducted in vitro, between Streptomyces sp. and a plant pathogen. However, recent research is starting to shed light on the behaviour of these biocontrol agents in planta, where the biotic and abiotic conditions share little similarity to those of controlled laboratory conditions. With a focus on specialised metabolites, this review details (i) the various methods by which Streptomyces biocontrol agents employ specialised metabolites as an additional line of defence against plant pathogens, (ii) the signals shared in the tripartite system of plant, pathogen and biocontrol agent, and (iii) an outlook on new approaches to expedite the identification and ecological understanding of these metabolites under a crop protection lens.
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spelling pubmed-103017232023-06-29 Streptomyces and their specialised metabolites for phytopathogen control – comparative in vitro and in planta metabolic approaches Dow, Lachlan Gallart, Marta Ramarajan, Margaret Law, Simon R. Thatcher, Louise F. Front Plant Sci Plant Science In the search for new crop protection microbial biocontrol agents, isolates from the genus Streptomyces are commonly found with promising attributes. Streptomyces are natural soil dwellers and have evolved as plant symbionts producing specialised metabolites with antibiotic and antifungal activities. Streptomyces biocontrol strains can effectively suppress plant pathogens via direct antimicrobial activity, but also induce plant resistance through indirect biosynthetic pathways. The investigation of factors stimulating the production and release of Streptomyces bioactive compounds is commonly conducted in vitro, between Streptomyces sp. and a plant pathogen. However, recent research is starting to shed light on the behaviour of these biocontrol agents in planta, where the biotic and abiotic conditions share little similarity to those of controlled laboratory conditions. With a focus on specialised metabolites, this review details (i) the various methods by which Streptomyces biocontrol agents employ specialised metabolites as an additional line of defence against plant pathogens, (ii) the signals shared in the tripartite system of plant, pathogen and biocontrol agent, and (iii) an outlook on new approaches to expedite the identification and ecological understanding of these metabolites under a crop protection lens. Frontiers Media S.A. 2023-06-14 /pmc/articles/PMC10301723/ /pubmed/37389291 http://dx.doi.org/10.3389/fpls.2023.1151912 Text en Copyright © 2023 Dow, Gallart, Ramarajan, Law and Thatcher https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Plant Science
Dow, Lachlan
Gallart, Marta
Ramarajan, Margaret
Law, Simon R.
Thatcher, Louise F.
Streptomyces and their specialised metabolites for phytopathogen control – comparative in vitro and in planta metabolic approaches
title Streptomyces and their specialised metabolites for phytopathogen control – comparative in vitro and in planta metabolic approaches
title_full Streptomyces and their specialised metabolites for phytopathogen control – comparative in vitro and in planta metabolic approaches
title_fullStr Streptomyces and their specialised metabolites for phytopathogen control – comparative in vitro and in planta metabolic approaches
title_full_unstemmed Streptomyces and their specialised metabolites for phytopathogen control – comparative in vitro and in planta metabolic approaches
title_short Streptomyces and their specialised metabolites for phytopathogen control – comparative in vitro and in planta metabolic approaches
title_sort streptomyces and their specialised metabolites for phytopathogen control – comparative in vitro and in planta metabolic approaches
topic Plant Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301723/
https://www.ncbi.nlm.nih.gov/pubmed/37389291
http://dx.doi.org/10.3389/fpls.2023.1151912
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