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What about the Cytoskeletal and Related Proteins of Tapeworms in the Host’s Immune Response? An Integrative Overview
Recent advances have increased our understanding of the molecular machinery in the cytoskeleton of mammalian cells, in contrast to the case of tapeworm parasites, where cytoskeleton remains poorly characterized. The pertinence of a better knowledge of the tapeworm cytoskeleton is linked to the medic...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302083/ https://www.ncbi.nlm.nih.gov/pubmed/37375530 http://dx.doi.org/10.3390/pathogens12060840 |
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author | Ríos-Valencia, Diana G. Ambrosio, Javier Tirado-Mendoza, Rocío Carrero, Julio César Laclette, Juan Pedro |
author_facet | Ríos-Valencia, Diana G. Ambrosio, Javier Tirado-Mendoza, Rocío Carrero, Julio César Laclette, Juan Pedro |
author_sort | Ríos-Valencia, Diana G. |
collection | PubMed |
description | Recent advances have increased our understanding of the molecular machinery in the cytoskeleton of mammalian cells, in contrast to the case of tapeworm parasites, where cytoskeleton remains poorly characterized. The pertinence of a better knowledge of the tapeworm cytoskeleton is linked to the medical importance of these parasitic diseases in humans and animal stock. Moreover, its study could offer new possibilities for the development of more effective anti-parasitic drugs, as well as better strategies for their surveillance, prevention, and control. In the present review, we compile the results of recent experiments on the cytoskeleton of these parasites and analyze how these novel findings might trigger the development of new drugs or the redesign of those currently used in addition to supporting their use as biomarkers in cutting-edge diagnostic tests. |
format | Online Article Text |
id | pubmed-10302083 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-103020832023-06-29 What about the Cytoskeletal and Related Proteins of Tapeworms in the Host’s Immune Response? An Integrative Overview Ríos-Valencia, Diana G. Ambrosio, Javier Tirado-Mendoza, Rocío Carrero, Julio César Laclette, Juan Pedro Pathogens Review Recent advances have increased our understanding of the molecular machinery in the cytoskeleton of mammalian cells, in contrast to the case of tapeworm parasites, where cytoskeleton remains poorly characterized. The pertinence of a better knowledge of the tapeworm cytoskeleton is linked to the medical importance of these parasitic diseases in humans and animal stock. Moreover, its study could offer new possibilities for the development of more effective anti-parasitic drugs, as well as better strategies for their surveillance, prevention, and control. In the present review, we compile the results of recent experiments on the cytoskeleton of these parasites and analyze how these novel findings might trigger the development of new drugs or the redesign of those currently used in addition to supporting their use as biomarkers in cutting-edge diagnostic tests. MDPI 2023-06-18 /pmc/articles/PMC10302083/ /pubmed/37375530 http://dx.doi.org/10.3390/pathogens12060840 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Ríos-Valencia, Diana G. Ambrosio, Javier Tirado-Mendoza, Rocío Carrero, Julio César Laclette, Juan Pedro What about the Cytoskeletal and Related Proteins of Tapeworms in the Host’s Immune Response? An Integrative Overview |
title | What about the Cytoskeletal and Related Proteins of Tapeworms in the Host’s Immune Response? An Integrative Overview |
title_full | What about the Cytoskeletal and Related Proteins of Tapeworms in the Host’s Immune Response? An Integrative Overview |
title_fullStr | What about the Cytoskeletal and Related Proteins of Tapeworms in the Host’s Immune Response? An Integrative Overview |
title_full_unstemmed | What about the Cytoskeletal and Related Proteins of Tapeworms in the Host’s Immune Response? An Integrative Overview |
title_short | What about the Cytoskeletal and Related Proteins of Tapeworms in the Host’s Immune Response? An Integrative Overview |
title_sort | what about the cytoskeletal and related proteins of tapeworms in the host’s immune response? an integrative overview |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302083/ https://www.ncbi.nlm.nih.gov/pubmed/37375530 http://dx.doi.org/10.3390/pathogens12060840 |
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