Cargando…

What about the Cytoskeletal and Related Proteins of Tapeworms in the Host’s Immune Response? An Integrative Overview

Recent advances have increased our understanding of the molecular machinery in the cytoskeleton of mammalian cells, in contrast to the case of tapeworm parasites, where cytoskeleton remains poorly characterized. The pertinence of a better knowledge of the tapeworm cytoskeleton is linked to the medic...

Descripción completa

Detalles Bibliográficos
Autores principales: Ríos-Valencia, Diana G., Ambrosio, Javier, Tirado-Mendoza, Rocío, Carrero, Julio César, Laclette, Juan Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302083/
https://www.ncbi.nlm.nih.gov/pubmed/37375530
http://dx.doi.org/10.3390/pathogens12060840
_version_ 1785064965571346432
author Ríos-Valencia, Diana G.
Ambrosio, Javier
Tirado-Mendoza, Rocío
Carrero, Julio César
Laclette, Juan Pedro
author_facet Ríos-Valencia, Diana G.
Ambrosio, Javier
Tirado-Mendoza, Rocío
Carrero, Julio César
Laclette, Juan Pedro
author_sort Ríos-Valencia, Diana G.
collection PubMed
description Recent advances have increased our understanding of the molecular machinery in the cytoskeleton of mammalian cells, in contrast to the case of tapeworm parasites, where cytoskeleton remains poorly characterized. The pertinence of a better knowledge of the tapeworm cytoskeleton is linked to the medical importance of these parasitic diseases in humans and animal stock. Moreover, its study could offer new possibilities for the development of more effective anti-parasitic drugs, as well as better strategies for their surveillance, prevention, and control. In the present review, we compile the results of recent experiments on the cytoskeleton of these parasites and analyze how these novel findings might trigger the development of new drugs or the redesign of those currently used in addition to supporting their use as biomarkers in cutting-edge diagnostic tests.
format Online
Article
Text
id pubmed-10302083
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-103020832023-06-29 What about the Cytoskeletal and Related Proteins of Tapeworms in the Host’s Immune Response? An Integrative Overview Ríos-Valencia, Diana G. Ambrosio, Javier Tirado-Mendoza, Rocío Carrero, Julio César Laclette, Juan Pedro Pathogens Review Recent advances have increased our understanding of the molecular machinery in the cytoskeleton of mammalian cells, in contrast to the case of tapeworm parasites, where cytoskeleton remains poorly characterized. The pertinence of a better knowledge of the tapeworm cytoskeleton is linked to the medical importance of these parasitic diseases in humans and animal stock. Moreover, its study could offer new possibilities for the development of more effective anti-parasitic drugs, as well as better strategies for their surveillance, prevention, and control. In the present review, we compile the results of recent experiments on the cytoskeleton of these parasites and analyze how these novel findings might trigger the development of new drugs or the redesign of those currently used in addition to supporting their use as biomarkers in cutting-edge diagnostic tests. MDPI 2023-06-18 /pmc/articles/PMC10302083/ /pubmed/37375530 http://dx.doi.org/10.3390/pathogens12060840 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Ríos-Valencia, Diana G.
Ambrosio, Javier
Tirado-Mendoza, Rocío
Carrero, Julio César
Laclette, Juan Pedro
What about the Cytoskeletal and Related Proteins of Tapeworms in the Host’s Immune Response? An Integrative Overview
title What about the Cytoskeletal and Related Proteins of Tapeworms in the Host’s Immune Response? An Integrative Overview
title_full What about the Cytoskeletal and Related Proteins of Tapeworms in the Host’s Immune Response? An Integrative Overview
title_fullStr What about the Cytoskeletal and Related Proteins of Tapeworms in the Host’s Immune Response? An Integrative Overview
title_full_unstemmed What about the Cytoskeletal and Related Proteins of Tapeworms in the Host’s Immune Response? An Integrative Overview
title_short What about the Cytoskeletal and Related Proteins of Tapeworms in the Host’s Immune Response? An Integrative Overview
title_sort what about the cytoskeletal and related proteins of tapeworms in the host’s immune response? an integrative overview
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302083/
https://www.ncbi.nlm.nih.gov/pubmed/37375530
http://dx.doi.org/10.3390/pathogens12060840
work_keys_str_mv AT riosvalenciadianag whataboutthecytoskeletalandrelatedproteinsoftapewormsinthehostsimmuneresponseanintegrativeoverview
AT ambrosiojavier whataboutthecytoskeletalandrelatedproteinsoftapewormsinthehostsimmuneresponseanintegrativeoverview
AT tiradomendozarocio whataboutthecytoskeletalandrelatedproteinsoftapewormsinthehostsimmuneresponseanintegrativeoverview
AT carrerojuliocesar whataboutthecytoskeletalandrelatedproteinsoftapewormsinthehostsimmuneresponseanintegrativeoverview
AT laclettejuanpedro whataboutthecytoskeletalandrelatedproteinsoftapewormsinthehostsimmuneresponseanintegrativeoverview