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Developing Transparent and Conductive PolyHEMA Gels Using Deep Eutectic Solvents
Poly(2-hydroxyethyl methacrylate) (polyHEMA) hydrogels are commonly used in biomaterials such as contact lenses. However, water evaporation from these hydrogels can cause discomfort to wearers, and the bulk polymerization method used to synthesize them often results in heterogeneous microstructures,...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302097/ https://www.ncbi.nlm.nih.gov/pubmed/37376251 http://dx.doi.org/10.3390/polym15122605 |
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author | Chen, Tai-Yu Jiang, Yi-Jie Chien, Hsiu-Wen |
author_facet | Chen, Tai-Yu Jiang, Yi-Jie Chien, Hsiu-Wen |
author_sort | Chen, Tai-Yu |
collection | PubMed |
description | Poly(2-hydroxyethyl methacrylate) (polyHEMA) hydrogels are commonly used in biomaterials such as contact lenses. However, water evaporation from these hydrogels can cause discomfort to wearers, and the bulk polymerization method used to synthesize them often results in heterogeneous microstructures, reducing their optical properties and elasticity. In this study, we synthesized polyHEMA gels using a deep eutectic solvent (DES) instead of water and compared their properties to traditional hydrogels. Fourier-transform infrared spectroscopy (FTIR) showed that HEMA conversion in DES was faster than in water. DES gels also demonstrated higher transparency, toughness, and conductivity, along with lower dehydration, than hydrogels. The compressive and tensile modulus values of DES gels increased with HEMA concentration. A DES gel with 45% HEMA showed excellent compression–relaxation cycles and had the highest strain at break value in the tensile test. Our findings suggest that DES is a promising alternative to water for synthesizing contact lenses with improved optical and mechanical properties. Furthermore, DES gels’ conduction properties may enable their application in biosensors. This study presents an innovative approach to synthesizing polyHEMA gels and provides insights into their potential applications in the biomaterials field. |
format | Online Article Text |
id | pubmed-10302097 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-103020972023-06-29 Developing Transparent and Conductive PolyHEMA Gels Using Deep Eutectic Solvents Chen, Tai-Yu Jiang, Yi-Jie Chien, Hsiu-Wen Polymers (Basel) Article Poly(2-hydroxyethyl methacrylate) (polyHEMA) hydrogels are commonly used in biomaterials such as contact lenses. However, water evaporation from these hydrogels can cause discomfort to wearers, and the bulk polymerization method used to synthesize them often results in heterogeneous microstructures, reducing their optical properties and elasticity. In this study, we synthesized polyHEMA gels using a deep eutectic solvent (DES) instead of water and compared their properties to traditional hydrogels. Fourier-transform infrared spectroscopy (FTIR) showed that HEMA conversion in DES was faster than in water. DES gels also demonstrated higher transparency, toughness, and conductivity, along with lower dehydration, than hydrogels. The compressive and tensile modulus values of DES gels increased with HEMA concentration. A DES gel with 45% HEMA showed excellent compression–relaxation cycles and had the highest strain at break value in the tensile test. Our findings suggest that DES is a promising alternative to water for synthesizing contact lenses with improved optical and mechanical properties. Furthermore, DES gels’ conduction properties may enable their application in biosensors. This study presents an innovative approach to synthesizing polyHEMA gels and provides insights into their potential applications in the biomaterials field. MDPI 2023-06-08 /pmc/articles/PMC10302097/ /pubmed/37376251 http://dx.doi.org/10.3390/polym15122605 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Chen, Tai-Yu Jiang, Yi-Jie Chien, Hsiu-Wen Developing Transparent and Conductive PolyHEMA Gels Using Deep Eutectic Solvents |
title | Developing Transparent and Conductive PolyHEMA Gels Using Deep Eutectic Solvents |
title_full | Developing Transparent and Conductive PolyHEMA Gels Using Deep Eutectic Solvents |
title_fullStr | Developing Transparent and Conductive PolyHEMA Gels Using Deep Eutectic Solvents |
title_full_unstemmed | Developing Transparent and Conductive PolyHEMA Gels Using Deep Eutectic Solvents |
title_short | Developing Transparent and Conductive PolyHEMA Gels Using Deep Eutectic Solvents |
title_sort | developing transparent and conductive polyhema gels using deep eutectic solvents |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302097/ https://www.ncbi.nlm.nih.gov/pubmed/37376251 http://dx.doi.org/10.3390/polym15122605 |
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