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Enhancing Cell Penetration Efficiency of Cyclic Oligoarginines Using Rigid Scaffolds
Delivering therapeutic agents into cells has always been a major challenge. In recent years, cyclization emerged as a tool for designing CPPs to increase their internalization and stability. Cyclic ring(s) can protect the peptide from enzymatic degradation, so cyclic peptides remain intact. Therefor...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302231/ https://www.ncbi.nlm.nih.gov/pubmed/37376184 http://dx.doi.org/10.3390/pharmaceutics15061736 |