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Influence of Surface-Modification via PEGylation or Chitosanization of Lipidic Nanocarriers on In Vivo Pharmacokinetic/Pharmacodynamic Profiles of Apixaban

Nanostructured lipid carriers (NLCs) have been proven to significantly improve the bioavailability and efficacy of many drugs; however, they still have many limitations. These limitations could hinder their potential for enhancing the bioavailability of poorly water-soluble drugs and, therefore, req...

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Detalles Bibliográficos
Autores principales:	Zaky, Mohamed F., Hammady, Taha M., Gad, Shadeed, Alattar, Abdullah, Alshaman, Reem, Hegazy, Ann, Zaitone, Sawsan A., Ghorab, Mamdouh Mostafa, Megahed, Mohamed A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302406/ https://www.ncbi.nlm.nih.gov/pubmed/37376116 http://dx.doi.org/10.3390/pharmaceutics15061668

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