Improved Therapeutic Delivery Targeting Clinically Relevant Orthotopic Human Pancreatic Tumors Engrafted in Immunocompromised Pigs Using Ultrasound-Induced Cavitation: A Pilot Study

Pancreatic tumors can be resistant to drug penetration due to high interstitial fluid pressure, dense stroma, and disarrayed vasculature. Ultrasound-induced cavitation is an emerging technology that may overcome many of these limitations. Low-intensity ultrasound, coupled with co-administered cavita...

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Detalles Bibliográficos
Autores principales: Imran, Khan Mohammad, Tintera, Benjamin, Morrison, Holly A., Tupik, Juselyn D., Nagai-Singer, Margaret A., Ivester, Hannah, Council-Troche, McAlister, Edwards, Michael, Coutermarsh-Ott, Sheryl, Byron, Christopher, Clark-Deener, Sherrie, Uh, Kyungjun, Lee, Kiho, Boulos, Paul, Rowe, Cliff, Coviello, Christian, Allen, Irving C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302458/
https://www.ncbi.nlm.nih.gov/pubmed/37376034
http://dx.doi.org/10.3390/pharmaceutics15061585

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