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Molecular Mechanism of Nucleosome Recognition by the Pioneer Transcription Factor Sox
[Image: see text] Pioneer transcription factors (PTFs) have the remarkable ability to directly bind to chromatin to stimulate vital cellular processes. In this work, we dissect the universal binding mode of Sox PTF by combining extensive molecular simulations and physiochemistry approaches, along wi...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302475/ https://www.ncbi.nlm.nih.gov/pubmed/37307148 http://dx.doi.org/10.1021/acs.jcim.2c01520 |