Molecular Mechanism of Nucleosome Recognition by the Pioneer Transcription Factor Sox

[Image: see text] Pioneer transcription factors (PTFs) have the remarkable ability to directly bind to chromatin to stimulate vital cellular processes. In this work, we dissect the universal binding mode of Sox PTF by combining extensive molecular simulations and physiochemistry approaches, along wi...

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Detalles Bibliográficos
Autores principales: Ozden, Burcu, Boopathi, Ramachandran, Barlas, Ayşe Berçin, Lone, Imtiaz N., Bednar, Jan, Petosa, Carlo, Kale, Seyit, Hamiche, Ali, Angelov, Dimitar, Dimitrov, Stefan, Karaca, Ezgi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302475/
https://www.ncbi.nlm.nih.gov/pubmed/37307148
http://dx.doi.org/10.1021/acs.jcim.2c01520

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