Optimizing the number of variants tracked to follow disease burden with circulating tumor DNA assays in metastatic colorectal cancer

BACKGROUND: The number of somatic mutations detectable in circulating tumor DNA (ctDNA) is highly heterogeneous in metastatic colorectal cancer (mCRC). The optimal number of mutations required to assess disease kinetics is relevant and remains poorly understood. OBJECTIVES: To determine whether incr...

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Detalles Bibliográficos
Autores principales: Boutin, Mélina, Topham, James T., Feilotter, Harriet, Kennecke, Hagen F., Couture, Félix, Harb, Mohammed, Kavan, Peter, Berry, Scott, Lim, Howard J., Goffin, John R., Ahmad, Chaudhary, Lott, Anthony, Renouf, Daniel J., Jonker, Derek J., Tu, Dongsheng, O’Callaghan, Chris J., Chen, Eric X., Loree, Jonathan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Liquid Biopsy in Gastrointestinal Cancers: circulating tumor DNA (ctDNA) and circulating tumor cell (CTC)-based precision oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302520/
https://www.ncbi.nlm.nih.gov/pubmed/37389190
http://dx.doi.org/10.1177/17588359231183682

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