USP39-mediated deubiquitination of Cyclin B1 promotes tumor cell proliferation and glioma progression

BACKGROUND: The elevated Cyclin B1 expression contributes to various tumorigenesis and poor prognosis. Cyclin B1 expression could be regulated by ubiquitination and deubiquitination. However, the mechanism of how Cyclin B1 is deubiquitinated and its roles in human glioma remain unclear. METHODS: Co-...

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Detalles Bibliográficos
Autores principales: Xiao, Yue, Chen, Xinyi, Hu, Weiwei, Ma, Wenjing, Di, Qianqian, Tang, Haimei, Zhao, Xibao, Huang, Guodong, Chen, Weilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302533/
https://www.ncbi.nlm.nih.gov/pubmed/37302347
http://dx.doi.org/10.1016/j.tranon.2023.101713

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