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Synthesis, Biophysical Properties, and Antitumor Activity of Antisense Oligonucleotides Conjugated with Anisamide

Antisense oligonucleotides (ASONs) have proven potential for the treatment of various diseases. However, their limited bioavailability restricts their clinical application. New structures with improved enzyme resistance stability and efficient drug delivery are needed. In this work, we propose a nov...

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Detalles Bibliográficos
Autores principales: Zhang, Zhe, Chen, Zuyi, Li, Cheng, Xiao, Zhenyu, Luo, Yuan, Pan, Xiaochen, Xu, Liang, Feng, Xuesong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302603/
https://www.ncbi.nlm.nih.gov/pubmed/37376093
http://dx.doi.org/10.3390/pharmaceutics15061645