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Synthesis, Biophysical Properties, and Antitumor Activity of Antisense Oligonucleotides Conjugated with Anisamide
Antisense oligonucleotides (ASONs) have proven potential for the treatment of various diseases. However, their limited bioavailability restricts their clinical application. New structures with improved enzyme resistance stability and efficient drug delivery are needed. In this work, we propose a nov...
Autores principales: | Zhang, Zhe, Chen, Zuyi, Li, Cheng, Xiao, Zhenyu, Luo, Yuan, Pan, Xiaochen, Xu, Liang, Feng, Xuesong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302603/ https://www.ncbi.nlm.nih.gov/pubmed/37376093 http://dx.doi.org/10.3390/pharmaceutics15061645 |
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