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Population Pharmacokinetic Analysis of Perampanel in Portuguese Patients Diagnosed with Refractory Epilepsy

Perampanel is a promising antiepileptic drug (AED) for refractory epilepsy treatment due to its innovative mechanism of action. This study aimed to develop a population pharmacokinetic (PopPK) model to be further used in initial dose optimization of perampanel in patients diagnosed with refractory e...

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Detalles Bibliográficos
Autores principales:	Silva, Rui, Colom, Helena, Bicker, Joana, Almeida, Anabela, Silva, Ana, Sales, Francisco, Santana, Isabel, Falcão, Amílcar, Fortuna, Ana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302681/ https://www.ncbi.nlm.nih.gov/pubmed/37376153 http://dx.doi.org/10.3390/pharmaceutics15061704

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