Development of a Gene and Nucleic Acid Delivery System for Skeletal Muscle Administration via Limb Perfusion Using Nanobubbles and Ultrasound

Strategies for gene and nucleic acid delivery to skeletal muscles have been extensively explored to treat Duchenne muscular dystrophy (DMD) and other neuromuscular diseases. Of these, effective intravascular delivery of naked plasmid DNA (pDNA) and nucleic acids into muscles is an attractive approac...

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Detalles Bibliográficos
Autores principales: Sekine, Shohko, Mayama, Sayaka, Nishijima, Nobuaki, Kojima, Takuo, Endo-Takahashi, Yoko, Ishii, Yuko, Shiono, Hitomi, Akiyama, Saki, Sakurai, Akane, Sashida, Sanae, Hamano, Nobuhito, Tada, Rui, Suzuki, Ryo, Maruyama, Kazuo, Negishi, Yoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302710/
https://www.ncbi.nlm.nih.gov/pubmed/37376113
http://dx.doi.org/10.3390/pharmaceutics15061665

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