Polyvalent Nano-Lectin Potently Neutralizes SARS-CoV-2 by Targeting Glycans on the Viral Spike Protein

[Image: see text] Mutations in spike (S) protein epitopes allow SARS-CoV-2 variants to evade antibody responses induced by infection and/or vaccination. In contrast, mutations in glycosylation sites across SARS-CoV-2 variants are very rare, making glycans a potential robust target for developing ant...

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Autores principales: Budhadev, Darshita, Hooper, James, Rocha, Cheila, Nehlmeier, Inga, Kempf, Amy Madeleine, Hoffmann, Markus, Krüger, Nadine, Zhou, Dejian, Pöhlmann, Stefan, Guo, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302749/
https://www.ncbi.nlm.nih.gov/pubmed/37388683
http://dx.doi.org/10.1021/jacsau.3c00163

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