Cargando…

Analysis of CRISPR/Cas Genetic Structure, Spacer Content and Molecular Epidemiology in Brazilian Acinetobacter baumannii Clinical Isolates

CRISPR/Cas is a molecular mechanism to prevent predatory viruses from invading bacteria via the insertion of small viral sequences (spacers) in its repetitive locus. The nature of spacer incorporation and the viral origins of spacers provide an overview of the genetic evolution of bacteria, their na...

Descripción completa

Detalles Bibliográficos
Autores principales:	Silva, Adrianne M. A., Luz, Ana C. O., Xavier, Keyla V. M., Barros, Maria P. S., Alves, Hirisleide B., Batista, Marcus V. A., Leal-Balbino, Tereza C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302819/ https://www.ncbi.nlm.nih.gov/pubmed/37375454 http://dx.doi.org/10.3390/pathogens12060764

Ejemplares similares

CRISPR-cas Subtype I-Fb in Acinetobacter baumannii: Evolution and Utilization for Strain Subtyping
por: Karah, Nabil, et al.
Publicado: (2015)

CRISPR-Cas9-Based Genome Editing and Cytidine Base Editing in Acinetobacter baumannii
por: Wang, Yu, et al.
Publicado: (2020)

CRISPR-Cas in Acinetobacter baumannii Contributes to Antibiotic Susceptibility by Targeting Endogenous AbaI
por: Wang, Yuhang, et al.
Publicado: (2022)

CRISPR-Cas Systems and the Paradox of Self-Targeting Spacers
por: Wimmer, Franziska, et al.
Publicado: (2020)

Cas1–Cas2 complex formation mediates spacer acquisition during CRISPR–Cas adaptive immunity
por: Nuñez, James K., et al.
Publicado: (2014)

Genomic and Phenotypic Analysis of Multidrug-Resistant Acinetobacter baumannii Clinical Isolates Carrying Different Types of CRISPR/Cas Systems
por: Tyumentseva, Marina, et al.
Publicado: (2021)

Real-time Observation of CRISPR spacer acquisition by Cas1–Cas2 integrase
por: Budhathoki, Jagat B., et al.
Publicado: (2020)

Integrase-mediated spacer acquisition during CRISPR–Cas adaptive immunity
por: Nuñez, James K., et al.
Publicado: (2015)

Spacer prioritization in CRISPR-Cas9 immunity is enabled by the leader RNA
por: Liao, Chunyu, et al.
Publicado: (2022)

Cas4 Facilitates PAM-Compatible Spacer Selection during CRISPR Adaptation
por: Kieper, Sebastian N., et al.
Publicado: (2018)

CRISPR-Based Gene Editing in Acinetobacter baumannii to Combat Antimicrobial Resistance
por: Junaid, Muhammad, et al.
Publicado: (2023)

On the Origin of Reverse Transcriptase-Using CRISPR-Cas Systems and Their Hyperdiverse, Enigmatic Spacer Repertoires
por: Silas, Sukrit, et al.
Publicado: (2017)

Probabilistic models for CRISPR spacer content evolution
por: Kupczok, Anne, et al.
Publicado: (2013)

Unique properties of spacer acquisition by the type III-A CRISPR-Cas system
por: Zhang, Xinfu, et al.
Publicado: (2021)

How Type II CRISPR-Cas establish immunity through Cas1-Cas2 mediated spacer integration
por: Xiao, Yibei, et al.
Publicado: (2017)

Comparative Genomics of Acinetobacter baumannii Clinical Strains From Brazil Reveals Polyclonal Dissemination and Selective Exchange of Mobile Genetic Elements Associated With Resistance Genes
por: Leal, Nilma C., et al.
Publicado: (2020)

Tackling Acinetobacter baumannii
por: Granata, Guido, et al.
Publicado: (2023)

Cas1 and Cas2 From the Type II-C CRISPR-Cas System of Riemerella anatipestifer Are Required for Spacer Acquisition
por: He, Yang, et al.
Publicado: (2018)

Detection and characterization of spacer integration intermediates in type I-E CRISPR–Cas system
por: Arslan, Zihni, et al.
Publicado: (2014)

Casposase structure and the mechanistic link between DNA transposition and spacer acquisition by CRISPR-Cas
por: Hickman, Alison B, et al.
Publicado: (2020)

Evaluation of Parameters for High Efficiency Transformation of Acinetobacter baumannii
por: Yildirim, Suleyman, et al.
Publicado: (2016)

Conserved motifs in the CRISPR leader sequence control spacer acquisition levels in Type I-D CRISPR-Cas systems
por: Kieper, Sebastian N, et al.
Publicado: (2019)

Molecular epidemiology and drug resistance of Acinetobacter baumannii isolated from a regional hospital in the Brazilian Amazon region
por: Ribeiro, Edlainny Araujo, et al.
Publicado: (2020)

First report of OXA-72 producing Acinetobacter baumannii in Romania
por: Georgescu, M., et al.
Publicado: (2016)

The Mechanisms of Disease Caused by Acinetobacter baumannii
por: Morris, Faye C., et al.
Publicado: (2019)

Structure of the DNA-Bound Spacer Capture Complex of a Type II CRISPR-Cas System
por: Wilkinson, Martin, et al.
Publicado: (2019)

Mechanism of spacer integration links the CRISPR/Cas system to transposition as a form of mobile DNA
por: Dyda, Fred, et al.
Publicado: (2015)

Spacer-length DNA intermediates are associated with Cas1 in cells undergoing primed CRISPR adaptation
por: Musharova, Olga, et al.
Publicado: (2017)

Spacer acquisition by Type III CRISPR–Cas system during bacteriophage infection of Thermus thermophilus
por: Artamonova, Daria, et al.
Publicado: (2020)

PAM-repeat associations and spacer selection preferences in single and co-occurring CRISPR-Cas systems
por: Vink, Jochem N. A., et al.
Publicado: (2021)

Different modes of spacer acquisition by the Staphylococcus epidermidis type III-A CRISPR-Cas system
por: Aviram, Naama, et al.
Publicado: (2022)

Multidrug-Resistant Acinetobacter baumannii
por: Abbo, Aharon, et al.
Publicado: (2005)

Multidrug-Resistant Acinetobacter baumannii
por: Krcmery, Vladimir, et al.
Publicado: (2007)

Diagnosis of Acinetobacter Baumannii Infections
por: Gozdas, Hasan T
Publicado: (2012)

Acinetobacter baumannii—The New MRSA?
por: Barrie, Alasdair, et al.
Publicado: (2016)

Glycosphingolipids Recognized by Acinetobacter baumannii
por: Madar Johansson, Miralda, et al.
Publicado: (2020)

Subunit vaccines for Acinetobacter baumannii
por: Yang, Ning, et al.
Publicado: (2023)

Carbapenem-resistant Acinetobacter baumannii outbreak at university hospital
por: Takagi, E.H., et al.
Publicado: (2009)

Natural diversity of CRISPR spacers of Thermus: evidence of local spacer acquisition and global spacer exchange
por: Lopatina, Anna, et al.
Publicado: (2019)

Whole-Genome Analysis of Acinetobacter baumannii Strain AB43 Containing a Type I-Fb CRISPR-Cas System: Insights into the Relationship with Drug Resistance
por: Guo, Tingting, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_qhs2kouo9coec7a17holanpn1f