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Biophysical Aspects of Neurodegenerative and Neurodevelopmental Disorders Involving Endo-/Lysosomal CLC Cl(−)/H(+) Antiporters

Endosomes and lysosomes are intracellular vesicular organelles with important roles in cell functions such as protein homeostasis, clearance of extracellular material, and autophagy. Endolysosomes are characterized by an acidic luminal pH that is critical for proper function. Five members of the gen...

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Detalles Bibliográficos
Autores principales: Coppola, Maria Antonietta, Tettey-Matey, Abraham, Imbrici, Paola, Gavazzo, Paola, Liantonio, Antonella, Pusch, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10303033/
https://www.ncbi.nlm.nih.gov/pubmed/37374100
http://dx.doi.org/10.3390/life13061317

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