Cargando…
In Silico Development of Novel Benzofuran-1,3,4-Oxadiazoles as Lead Inhibitors of M. tuberculosis Polyketide Synthase 13
Benzofuran and 1,3,4-oxadiazole are privileged and versatile heterocyclic pharmacophores which display a broad spectrum of biological and pharmacological therapeutic potential against a wide variety of diseases. This article reports in silico CADD (computer-aided drug design) and molecular hybridiza...
Autores principales: | Irfan, Ali, Faisal, Shah, Zahoor, Ameer Fawad, Noreen, Razia, Al-Hussain, Sami A., Tuzun, Burak, Javaid, Rakshanda, Elhenawy, Ahmed A., Zaki, Magdi E. A., Ahmad, Sajjad, Abdellattif, Magda H. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10303075/ https://www.ncbi.nlm.nih.gov/pubmed/37375776 http://dx.doi.org/10.3390/ph16060829 |
Ejemplares similares
-
An Exploration of the Inhibitory Mechanism of Rationally Screened Benzofuran-1,3,4-Oxadiazoles and-1,2,4-Triazoles as Inhibitors of NS5B RdRp Hepatitis C Virus through Pharmacoinformatic Approaches
por: Irfan, Ali, et al.
Publicado: (2023) -
Structure-Based Virtual Screening of Furan-1,3,4-Oxadiazole Tethered N-phenylacetamide Derivatives as Novel Class of hTYR and hTYRP1 Inhibitors
por: Irfan, Ali, et al.
Publicado: (2023) -
Ultrasonic-Assisted Synthesis of Benzofuran Appended Oxadiazole Molecules as Tyrosinase Inhibitors: Mechanistic Approach through Enzyme Inhibition, Molecular Docking, Chemoinformatics, ADMET and Drug-Likeness Studies
por: Irfan, Ali, et al.
Publicado: (2022) -
BTEAC Catalyzed Ultrasonic-Assisted Synthesis of Bromobenzofuran-Oxadiazoles: Unravelling Anti-HepG-2 Cancer Therapeutic Potential through In Vitro and In Silico Studies
por: Irfan, Ali, et al.
Publicado: (2023) -
Exploring the Synergistic Anticancer Potential of Benzofuran–Oxadiazoles and Triazoles: Improved Ultrasound- and Microwave-Assisted Synthesis, Molecular Docking, Hemolytic, Thrombolytic and Anticancer Evaluation of Furan-Based Molecules
por: Irfan, Ali, et al.
Publicado: (2022)