Cargando…
Seroprevalence of Epizootic Hemorrhagic Disease Virus in Guangdong Cattle Farms during 2013–2017, China
Epizootic hemorrhagic disease (EHD) is an infectious viral disease caused by epizootic hemorrhagic disease virus (EHDV) and EHDV frequently circulates in wild and domestic ruminants. Sporadic outbreaks of EHD have caused thousands of deaths and stillbirths on cattle farms. However, not much is known...
Autores principales: | , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10303234/ https://www.ncbi.nlm.nih.gov/pubmed/37376563 http://dx.doi.org/10.3390/v15061263 |
_version_ | 1785065230547550208 |
---|---|
author | Lv, Min-Na Zhu, Jian-Bo Liao, Shen-Quan Yang, Zhen-Xing Lin, Xu-Hui Qi, Nan-Shan Chen, Qin-Ling Wu, Cai-Yan Li, Juan Cai, Hai-Ming Zhang, Jian-Fei Hu, Jun-Jing Xiao, Wen-Wan Zhang, Xu Sun, Ming-Fei |
author_facet | Lv, Min-Na Zhu, Jian-Bo Liao, Shen-Quan Yang, Zhen-Xing Lin, Xu-Hui Qi, Nan-Shan Chen, Qin-Ling Wu, Cai-Yan Li, Juan Cai, Hai-Ming Zhang, Jian-Fei Hu, Jun-Jing Xiao, Wen-Wan Zhang, Xu Sun, Ming-Fei |
author_sort | Lv, Min-Na |
collection | PubMed |
description | Epizootic hemorrhagic disease (EHD) is an infectious viral disease caused by epizootic hemorrhagic disease virus (EHDV) and EHDV frequently circulates in wild and domestic ruminants. Sporadic outbreaks of EHD have caused thousands of deaths and stillbirths on cattle farms. However, not much is known about the circulating status of EHDV in Guangdong, southern China. To estimate the seroprevalence of EHDV in Guangdong province, 2886 cattle serum samples were collected from 2013 to 2017 and tested for antibodies against EHDV using a competitive ELISA. The overall seroprevalence of EHDV reached 57.87% and was highest in autumn (75.34%). A subset of positive samples were serotyped by a serum neutralization test, showing that EHDV serotypes 1 and 5–8 were circulating in Guangdong. In addition, EHDV prevalence always peaked in autumn, while eastern Guangdong had the highest EHDV seropositivity over the five-year period, displaying apparent temporal–spatial distribution of EHDV prevalence. A binary logistic model analysis indicated a significant association between cattle with BTV infections and seroprevalence of EHDV (OR = 1.70, p < 0.001). The co-infection of different serotypes of EHDV and BTV raises a high risk of potential genomic reassortment and is likely to pose a significant threat to cattle, thus urging more surveillance to monitor their circulating dynamics in China. |
format | Online Article Text |
id | pubmed-10303234 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-103032342023-06-29 Seroprevalence of Epizootic Hemorrhagic Disease Virus in Guangdong Cattle Farms during 2013–2017, China Lv, Min-Na Zhu, Jian-Bo Liao, Shen-Quan Yang, Zhen-Xing Lin, Xu-Hui Qi, Nan-Shan Chen, Qin-Ling Wu, Cai-Yan Li, Juan Cai, Hai-Ming Zhang, Jian-Fei Hu, Jun-Jing Xiao, Wen-Wan Zhang, Xu Sun, Ming-Fei Viruses Article Epizootic hemorrhagic disease (EHD) is an infectious viral disease caused by epizootic hemorrhagic disease virus (EHDV) and EHDV frequently circulates in wild and domestic ruminants. Sporadic outbreaks of EHD have caused thousands of deaths and stillbirths on cattle farms. However, not much is known about the circulating status of EHDV in Guangdong, southern China. To estimate the seroprevalence of EHDV in Guangdong province, 2886 cattle serum samples were collected from 2013 to 2017 and tested for antibodies against EHDV using a competitive ELISA. The overall seroprevalence of EHDV reached 57.87% and was highest in autumn (75.34%). A subset of positive samples were serotyped by a serum neutralization test, showing that EHDV serotypes 1 and 5–8 were circulating in Guangdong. In addition, EHDV prevalence always peaked in autumn, while eastern Guangdong had the highest EHDV seropositivity over the five-year period, displaying apparent temporal–spatial distribution of EHDV prevalence. A binary logistic model analysis indicated a significant association between cattle with BTV infections and seroprevalence of EHDV (OR = 1.70, p < 0.001). The co-infection of different serotypes of EHDV and BTV raises a high risk of potential genomic reassortment and is likely to pose a significant threat to cattle, thus urging more surveillance to monitor their circulating dynamics in China. MDPI 2023-05-28 /pmc/articles/PMC10303234/ /pubmed/37376563 http://dx.doi.org/10.3390/v15061263 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Lv, Min-Na Zhu, Jian-Bo Liao, Shen-Quan Yang, Zhen-Xing Lin, Xu-Hui Qi, Nan-Shan Chen, Qin-Ling Wu, Cai-Yan Li, Juan Cai, Hai-Ming Zhang, Jian-Fei Hu, Jun-Jing Xiao, Wen-Wan Zhang, Xu Sun, Ming-Fei Seroprevalence of Epizootic Hemorrhagic Disease Virus in Guangdong Cattle Farms during 2013–2017, China |
title | Seroprevalence of Epizootic Hemorrhagic Disease Virus in Guangdong Cattle Farms during 2013–2017, China |
title_full | Seroprevalence of Epizootic Hemorrhagic Disease Virus in Guangdong Cattle Farms during 2013–2017, China |
title_fullStr | Seroprevalence of Epizootic Hemorrhagic Disease Virus in Guangdong Cattle Farms during 2013–2017, China |
title_full_unstemmed | Seroprevalence of Epizootic Hemorrhagic Disease Virus in Guangdong Cattle Farms during 2013–2017, China |
title_short | Seroprevalence of Epizootic Hemorrhagic Disease Virus in Guangdong Cattle Farms during 2013–2017, China |
title_sort | seroprevalence of epizootic hemorrhagic disease virus in guangdong cattle farms during 2013–2017, china |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10303234/ https://www.ncbi.nlm.nih.gov/pubmed/37376563 http://dx.doi.org/10.3390/v15061263 |
work_keys_str_mv | AT lvminna seroprevalenceofepizootichemorrhagicdiseasevirusinguangdongcattlefarmsduring20132017china AT zhujianbo seroprevalenceofepizootichemorrhagicdiseasevirusinguangdongcattlefarmsduring20132017china AT liaoshenquan seroprevalenceofepizootichemorrhagicdiseasevirusinguangdongcattlefarmsduring20132017china AT yangzhenxing seroprevalenceofepizootichemorrhagicdiseasevirusinguangdongcattlefarmsduring20132017china AT linxuhui seroprevalenceofepizootichemorrhagicdiseasevirusinguangdongcattlefarmsduring20132017china AT qinanshan seroprevalenceofepizootichemorrhagicdiseasevirusinguangdongcattlefarmsduring20132017china AT chenqinling seroprevalenceofepizootichemorrhagicdiseasevirusinguangdongcattlefarmsduring20132017china AT wucaiyan seroprevalenceofepizootichemorrhagicdiseasevirusinguangdongcattlefarmsduring20132017china AT lijuan seroprevalenceofepizootichemorrhagicdiseasevirusinguangdongcattlefarmsduring20132017china AT caihaiming seroprevalenceofepizootichemorrhagicdiseasevirusinguangdongcattlefarmsduring20132017china AT zhangjianfei seroprevalenceofepizootichemorrhagicdiseasevirusinguangdongcattlefarmsduring20132017china AT hujunjing seroprevalenceofepizootichemorrhagicdiseasevirusinguangdongcattlefarmsduring20132017china AT xiaowenwan seroprevalenceofepizootichemorrhagicdiseasevirusinguangdongcattlefarmsduring20132017china AT zhangxu seroprevalenceofepizootichemorrhagicdiseasevirusinguangdongcattlefarmsduring20132017china AT sunmingfei seroprevalenceofepizootichemorrhagicdiseasevirusinguangdongcattlefarmsduring20132017china |