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Seroprevalence of Epizootic Hemorrhagic Disease Virus in Guangdong Cattle Farms during 2013–2017, China

Epizootic hemorrhagic disease (EHD) is an infectious viral disease caused by epizootic hemorrhagic disease virus (EHDV) and EHDV frequently circulates in wild and domestic ruminants. Sporadic outbreaks of EHD have caused thousands of deaths and stillbirths on cattle farms. However, not much is known...

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Autores principales: Lv, Min-Na, Zhu, Jian-Bo, Liao, Shen-Quan, Yang, Zhen-Xing, Lin, Xu-Hui, Qi, Nan-Shan, Chen, Qin-Ling, Wu, Cai-Yan, Li, Juan, Cai, Hai-Ming, Zhang, Jian-Fei, Hu, Jun-Jing, Xiao, Wen-Wan, Zhang, Xu, Sun, Ming-Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10303234/
https://www.ncbi.nlm.nih.gov/pubmed/37376563
http://dx.doi.org/10.3390/v15061263
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author Lv, Min-Na
Zhu, Jian-Bo
Liao, Shen-Quan
Yang, Zhen-Xing
Lin, Xu-Hui
Qi, Nan-Shan
Chen, Qin-Ling
Wu, Cai-Yan
Li, Juan
Cai, Hai-Ming
Zhang, Jian-Fei
Hu, Jun-Jing
Xiao, Wen-Wan
Zhang, Xu
Sun, Ming-Fei
author_facet Lv, Min-Na
Zhu, Jian-Bo
Liao, Shen-Quan
Yang, Zhen-Xing
Lin, Xu-Hui
Qi, Nan-Shan
Chen, Qin-Ling
Wu, Cai-Yan
Li, Juan
Cai, Hai-Ming
Zhang, Jian-Fei
Hu, Jun-Jing
Xiao, Wen-Wan
Zhang, Xu
Sun, Ming-Fei
author_sort Lv, Min-Na
collection PubMed
description Epizootic hemorrhagic disease (EHD) is an infectious viral disease caused by epizootic hemorrhagic disease virus (EHDV) and EHDV frequently circulates in wild and domestic ruminants. Sporadic outbreaks of EHD have caused thousands of deaths and stillbirths on cattle farms. However, not much is known about the circulating status of EHDV in Guangdong, southern China. To estimate the seroprevalence of EHDV in Guangdong province, 2886 cattle serum samples were collected from 2013 to 2017 and tested for antibodies against EHDV using a competitive ELISA. The overall seroprevalence of EHDV reached 57.87% and was highest in autumn (75.34%). A subset of positive samples were serotyped by a serum neutralization test, showing that EHDV serotypes 1 and 5–8 were circulating in Guangdong. In addition, EHDV prevalence always peaked in autumn, while eastern Guangdong had the highest EHDV seropositivity over the five-year period, displaying apparent temporal–spatial distribution of EHDV prevalence. A binary logistic model analysis indicated a significant association between cattle with BTV infections and seroprevalence of EHDV (OR = 1.70, p < 0.001). The co-infection of different serotypes of EHDV and BTV raises a high risk of potential genomic reassortment and is likely to pose a significant threat to cattle, thus urging more surveillance to monitor their circulating dynamics in China.
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spelling pubmed-103032342023-06-29 Seroprevalence of Epizootic Hemorrhagic Disease Virus in Guangdong Cattle Farms during 2013–2017, China Lv, Min-Na Zhu, Jian-Bo Liao, Shen-Quan Yang, Zhen-Xing Lin, Xu-Hui Qi, Nan-Shan Chen, Qin-Ling Wu, Cai-Yan Li, Juan Cai, Hai-Ming Zhang, Jian-Fei Hu, Jun-Jing Xiao, Wen-Wan Zhang, Xu Sun, Ming-Fei Viruses Article Epizootic hemorrhagic disease (EHD) is an infectious viral disease caused by epizootic hemorrhagic disease virus (EHDV) and EHDV frequently circulates in wild and domestic ruminants. Sporadic outbreaks of EHD have caused thousands of deaths and stillbirths on cattle farms. However, not much is known about the circulating status of EHDV in Guangdong, southern China. To estimate the seroprevalence of EHDV in Guangdong province, 2886 cattle serum samples were collected from 2013 to 2017 and tested for antibodies against EHDV using a competitive ELISA. The overall seroprevalence of EHDV reached 57.87% and was highest in autumn (75.34%). A subset of positive samples were serotyped by a serum neutralization test, showing that EHDV serotypes 1 and 5–8 were circulating in Guangdong. In addition, EHDV prevalence always peaked in autumn, while eastern Guangdong had the highest EHDV seropositivity over the five-year period, displaying apparent temporal–spatial distribution of EHDV prevalence. A binary logistic model analysis indicated a significant association between cattle with BTV infections and seroprevalence of EHDV (OR = 1.70, p < 0.001). The co-infection of different serotypes of EHDV and BTV raises a high risk of potential genomic reassortment and is likely to pose a significant threat to cattle, thus urging more surveillance to monitor their circulating dynamics in China. MDPI 2023-05-28 /pmc/articles/PMC10303234/ /pubmed/37376563 http://dx.doi.org/10.3390/v15061263 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Lv, Min-Na
Zhu, Jian-Bo
Liao, Shen-Quan
Yang, Zhen-Xing
Lin, Xu-Hui
Qi, Nan-Shan
Chen, Qin-Ling
Wu, Cai-Yan
Li, Juan
Cai, Hai-Ming
Zhang, Jian-Fei
Hu, Jun-Jing
Xiao, Wen-Wan
Zhang, Xu
Sun, Ming-Fei
Seroprevalence of Epizootic Hemorrhagic Disease Virus in Guangdong Cattle Farms during 2013–2017, China
title Seroprevalence of Epizootic Hemorrhagic Disease Virus in Guangdong Cattle Farms during 2013–2017, China
title_full Seroprevalence of Epizootic Hemorrhagic Disease Virus in Guangdong Cattle Farms during 2013–2017, China
title_fullStr Seroprevalence of Epizootic Hemorrhagic Disease Virus in Guangdong Cattle Farms during 2013–2017, China
title_full_unstemmed Seroprevalence of Epizootic Hemorrhagic Disease Virus in Guangdong Cattle Farms during 2013–2017, China
title_short Seroprevalence of Epizootic Hemorrhagic Disease Virus in Guangdong Cattle Farms during 2013–2017, China
title_sort seroprevalence of epizootic hemorrhagic disease virus in guangdong cattle farms during 2013–2017, china
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10303234/
https://www.ncbi.nlm.nih.gov/pubmed/37376563
http://dx.doi.org/10.3390/v15061263
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