Novel Oleanolic Acid-Phtalimidines Tethered 1,2,3 Triazole Hybrids as Promising Antibacterial Agents: Design, Synthesis, In Vitro Experiments and In Silico Docking Studies

As part of the valorization of agricultural waste into bioactive compounds, a series of structurally novel oleanolic acid ((3β-hydroxyolean-12-en-28-oic acid, OA-1)-phtalimidines (isoindolinones) conjugates 18a–u bearing 1,2,3-triazole moieties were designed and synthesized by treating an azide 4 pr...

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Detalles Bibliográficos
Autores principales: Lahmadi, Ghofrane, Horchani, Mabrouk, Dbeibia, Amal, Mahdhi, Abdelkarim, Romdhane, Anis, Lawson, Ata Martin, Daïch, Adam, Harrath, Abdel Halim, Ben Jannet, Hichem, Othman, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10303287/
https://www.ncbi.nlm.nih.gov/pubmed/37375209
http://dx.doi.org/10.3390/molecules28124655

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10303287/
https://www.ncbi.nlm.nih.gov/pubmed/37375209
http://dx.doi.org/10.3390/molecules28124655

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