Tumor-secreted IFI35 promotes proliferation and cytotoxic activity of CD8(+) T cells through PI3K/AKT/mTOR signaling pathway in colorectal cancer

BACKGROUND: A large proportion of the patients with cancer do not respond to immunotherapies. Recent studies suggested an important role for tumor-infiltrating cytotoxic T lymphocytes (CTL) in enhancing response to immunotherapy. Here, we aim to identify gene that induce proliferative and cytotoxic...

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Detalles Bibliográficos
Autores principales: Li, Peisi, Zhou, Dawang, Chen, Dongwen, Cheng, Yikan, Chen, Yuan, Lin, Zhensen, Zhang, Xi, Huang, Zhihong, Cai, Jiawei, Huang, Wenfeng, Lin, Yanyun, Ke, Haoxian, Long, Jiahui, Zou, Yifeng, Ye, Shubiao, Lan, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10303345/
https://www.ncbi.nlm.nih.gov/pubmed/37380972
http://dx.doi.org/10.1186/s12929-023-00930-6

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