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Diagnostic and Therapeutic Strategy for Vagal Schwannoma: Case Series and Literature Review

Background and Objectives: Clinical management of vagal schwannoma is a real diagnostic and therapeutic challenge because the medical history and clinical examination are often non-specific and vagal nerve injury following surgical resection still represents an unsolved problem. The aim of this pape...

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Autores principales: Loperfido, Antonella, Celebrini, Alessandra, Fionda, Bruno, Bellocchi, Gianluca, Cristalli, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10303656/
https://www.ncbi.nlm.nih.gov/pubmed/37374217
http://dx.doi.org/10.3390/medicina59061013
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author Loperfido, Antonella
Celebrini, Alessandra
Fionda, Bruno
Bellocchi, Gianluca
Cristalli, Giovanni
author_facet Loperfido, Antonella
Celebrini, Alessandra
Fionda, Bruno
Bellocchi, Gianluca
Cristalli, Giovanni
author_sort Loperfido, Antonella
collection PubMed
description Background and Objectives: Clinical management of vagal schwannoma is a real diagnostic and therapeutic challenge because the medical history and clinical examination are often non-specific and vagal nerve injury following surgical resection still represents an unsolved problem. The aim of this paper is to provide a case series along with a diagnostic and therapeutic algorithm for vagal schwannoma of the head and neck, combining our experience with clinical evidence available in the literature. Materials and Methods: We retrospectively analyzed a series of patients affected by vagal schwannoma who were treated between 2000 and 2020. In addition, a review of the literature on vagal schwannoma management was conducted. Based on the cases described and the literature review, we made a diagnostic and therapeutic algorithm for the management of vagal schwannoma. Results: We were able to identify 10 patients affected by vagal schwannoma and treated between 2000 and 2020. All patients presented with a painless, mobile, slow-growing lateral neck mass with onset varying from a few months to years. The preoperative diagnostic workup included ultrasound (US) in nine cases, computed tomography (CT) with contrast in six patients and magnetic resonance imaging (MRI) of the neck in seven cases. All patients included in this study were surgically treated. Conclusions: Vagal schwannoma management represents a true challenge for clinicians and surgery is currently the most effective therapeutic strategy. A multidisciplinary approach through the collaboration of otolaryngologist with other specialists is desirable to develop a tailored treatment plan for the patient.
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spelling pubmed-103036562023-06-29 Diagnostic and Therapeutic Strategy for Vagal Schwannoma: Case Series and Literature Review Loperfido, Antonella Celebrini, Alessandra Fionda, Bruno Bellocchi, Gianluca Cristalli, Giovanni Medicina (Kaunas) Article Background and Objectives: Clinical management of vagal schwannoma is a real diagnostic and therapeutic challenge because the medical history and clinical examination are often non-specific and vagal nerve injury following surgical resection still represents an unsolved problem. The aim of this paper is to provide a case series along with a diagnostic and therapeutic algorithm for vagal schwannoma of the head and neck, combining our experience with clinical evidence available in the literature. Materials and Methods: We retrospectively analyzed a series of patients affected by vagal schwannoma who were treated between 2000 and 2020. In addition, a review of the literature on vagal schwannoma management was conducted. Based on the cases described and the literature review, we made a diagnostic and therapeutic algorithm for the management of vagal schwannoma. Results: We were able to identify 10 patients affected by vagal schwannoma and treated between 2000 and 2020. All patients presented with a painless, mobile, slow-growing lateral neck mass with onset varying from a few months to years. The preoperative diagnostic workup included ultrasound (US) in nine cases, computed tomography (CT) with contrast in six patients and magnetic resonance imaging (MRI) of the neck in seven cases. All patients included in this study were surgically treated. Conclusions: Vagal schwannoma management represents a true challenge for clinicians and surgery is currently the most effective therapeutic strategy. A multidisciplinary approach through the collaboration of otolaryngologist with other specialists is desirable to develop a tailored treatment plan for the patient. MDPI 2023-05-24 /pmc/articles/PMC10303656/ /pubmed/37374217 http://dx.doi.org/10.3390/medicina59061013 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Loperfido, Antonella
Celebrini, Alessandra
Fionda, Bruno
Bellocchi, Gianluca
Cristalli, Giovanni
Diagnostic and Therapeutic Strategy for Vagal Schwannoma: Case Series and Literature Review
title Diagnostic and Therapeutic Strategy for Vagal Schwannoma: Case Series and Literature Review
title_full Diagnostic and Therapeutic Strategy for Vagal Schwannoma: Case Series and Literature Review
title_fullStr Diagnostic and Therapeutic Strategy for Vagal Schwannoma: Case Series and Literature Review
title_full_unstemmed Diagnostic and Therapeutic Strategy for Vagal Schwannoma: Case Series and Literature Review
title_short Diagnostic and Therapeutic Strategy for Vagal Schwannoma: Case Series and Literature Review
title_sort diagnostic and therapeutic strategy for vagal schwannoma: case series and literature review
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10303656/
https://www.ncbi.nlm.nih.gov/pubmed/37374217
http://dx.doi.org/10.3390/medicina59061013
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