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Quantification of hematopoietic stem and progenitor cells by targeted DNA methylation analysis

Hematopoietic stem and progenitor cells (HSPCs) are quantified in daily clinical practice by flow cytometry. In this study, we provide proof of concept that HSPCs can also be estimated by targeted DNA methylation (DNAm) analysis. The DNAm levels at three individual CG dinucleotides (CpG sites) in th...

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Detalles Bibliográficos
Autores principales: Bocova, Ledio, Hubens, Wouter, Engel, Cordula, Koschmieder, Steffen, Jost, Edgar, Wagner, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10303729/
https://www.ncbi.nlm.nih.gov/pubmed/37370186
http://dx.doi.org/10.1186/s13148-023-01521-w