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High DNA methylation age deceleration defines an aggressive phenotype with immunoexclusion environments in endometrial carcinoma

Like telomere shortening, global DNA hypomethylation occurs progressively with cellular divisions or in vivo aging and functions as a mitotic clock to restrain malignant transformation/progression. Several DNA-methylation (DNAm) age clocks have been established to precisely predict chronological age...

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Detalles Bibliográficos
Autores principales: Hao, Jing, Liu, Tiantian, Xiu, Yuchen, Yuan, Huiyang, Xu, Dawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10303802/
https://www.ncbi.nlm.nih.gov/pubmed/37388735
http://dx.doi.org/10.3389/fimmu.2023.1208223