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High DNA methylation age deceleration defines an aggressive phenotype with immunoexclusion environments in endometrial carcinoma
Like telomere shortening, global DNA hypomethylation occurs progressively with cellular divisions or in vivo aging and functions as a mitotic clock to restrain malignant transformation/progression. Several DNA-methylation (DNAm) age clocks have been established to precisely predict chronological age...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10303802/ https://www.ncbi.nlm.nih.gov/pubmed/37388735 http://dx.doi.org/10.3389/fimmu.2023.1208223 |