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PD-1(Hi) CAR-T cells provide superior protection against solid tumors

Chimeric antigen receptor (CAR)-T cell therapy has emerged as a promising treatment option for several hematologic cancers. However, efforts to achieve the same level of therapeutic success in solid tumors have largely failed mainly due to CAR-T cell exhaustion and poor persistence at the tumor site...

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Detalles Bibliográficos
Autores principales:	Sailer, Cooper J., Hong, Yeonsun, Dahal, Ankit, Ryan, Allison T., Mir, Sana, Gerber, Scott A., Reagan, Patrick M., Kim, Minsoo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10303811/ https://www.ncbi.nlm.nih.gov/pubmed/37388744 http://dx.doi.org/10.3389/fimmu.2023.1187850

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