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An integrated full-head OPM-MEG system based on 128 zero-field sensors

Compact optically-pumped magnetometers (OPMs) are now commercially available with noise floors reaching 10 fT/Hz(1/2). However, to be used effectively for magnetoencephalography (MEG), dense arrays of these sensors are required to operate as an integrated turn-key system. In this study, we present t...

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Autores principales: Alem, Orang, Hughes, K. Jeramy, Buard, Isabelle, Cheung, Teresa P., Maydew, Tyler, Griesshammer, Andreas, Holloway, Kendall, Park, Aaron, Lechuga, Vanessa, Coolidge, Collin, Gerginov, Marja, Quigg, Erik, Seames, Alexander, Kronberg, Eugene, Teale, Peter, Knappe, Svenja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10303922/
https://www.ncbi.nlm.nih.gov/pubmed/37389367
http://dx.doi.org/10.3389/fnins.2023.1190310
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author Alem, Orang
Hughes, K. Jeramy
Buard, Isabelle
Cheung, Teresa P.
Maydew, Tyler
Griesshammer, Andreas
Holloway, Kendall
Park, Aaron
Lechuga, Vanessa
Coolidge, Collin
Gerginov, Marja
Quigg, Erik
Seames, Alexander
Kronberg, Eugene
Teale, Peter
Knappe, Svenja
author_facet Alem, Orang
Hughes, K. Jeramy
Buard, Isabelle
Cheung, Teresa P.
Maydew, Tyler
Griesshammer, Andreas
Holloway, Kendall
Park, Aaron
Lechuga, Vanessa
Coolidge, Collin
Gerginov, Marja
Quigg, Erik
Seames, Alexander
Kronberg, Eugene
Teale, Peter
Knappe, Svenja
author_sort Alem, Orang
collection PubMed
description Compact optically-pumped magnetometers (OPMs) are now commercially available with noise floors reaching 10 fT/Hz(1/2). However, to be used effectively for magnetoencephalography (MEG), dense arrays of these sensors are required to operate as an integrated turn-key system. In this study, we present the HEDscan, a 128-sensor OPM MEG system by FieldLine Medical, and evaluate its sensor performance with regard to bandwidth, linearity, and crosstalk. We report results from cross-validation studies with conventional cryogenic MEG, the Magnes 3,600 WH Biomagnetometer by 4-D Neuroimaging. Our results show high signal amplitudes captured by the OPM-MEG system during a standard auditory paradigm, where short tones at 1000 Hz were presented to the left ear of six healthy adult volunteers. We validate these findings through an event-related beamformer analysis, which is in line with existing literature results.
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spelling pubmed-103039222023-06-29 An integrated full-head OPM-MEG system based on 128 zero-field sensors Alem, Orang Hughes, K. Jeramy Buard, Isabelle Cheung, Teresa P. Maydew, Tyler Griesshammer, Andreas Holloway, Kendall Park, Aaron Lechuga, Vanessa Coolidge, Collin Gerginov, Marja Quigg, Erik Seames, Alexander Kronberg, Eugene Teale, Peter Knappe, Svenja Front Neurosci Neuroscience Compact optically-pumped magnetometers (OPMs) are now commercially available with noise floors reaching 10 fT/Hz(1/2). However, to be used effectively for magnetoencephalography (MEG), dense arrays of these sensors are required to operate as an integrated turn-key system. In this study, we present the HEDscan, a 128-sensor OPM MEG system by FieldLine Medical, and evaluate its sensor performance with regard to bandwidth, linearity, and crosstalk. We report results from cross-validation studies with conventional cryogenic MEG, the Magnes 3,600 WH Biomagnetometer by 4-D Neuroimaging. Our results show high signal amplitudes captured by the OPM-MEG system during a standard auditory paradigm, where short tones at 1000 Hz were presented to the left ear of six healthy adult volunteers. We validate these findings through an event-related beamformer analysis, which is in line with existing literature results. Frontiers Media S.A. 2023-06-14 /pmc/articles/PMC10303922/ /pubmed/37389367 http://dx.doi.org/10.3389/fnins.2023.1190310 Text en Copyright © 2023 Alem, Hughes, Buard, Cheung, Maydew, Griesshammer, Holloway, Park, Lechuga, Coolidge, Gerginov, Quigg, Seames, Kronberg, Teale and Knappe. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Alem, Orang
Hughes, K. Jeramy
Buard, Isabelle
Cheung, Teresa P.
Maydew, Tyler
Griesshammer, Andreas
Holloway, Kendall
Park, Aaron
Lechuga, Vanessa
Coolidge, Collin
Gerginov, Marja
Quigg, Erik
Seames, Alexander
Kronberg, Eugene
Teale, Peter
Knappe, Svenja
An integrated full-head OPM-MEG system based on 128 zero-field sensors
title An integrated full-head OPM-MEG system based on 128 zero-field sensors
title_full An integrated full-head OPM-MEG system based on 128 zero-field sensors
title_fullStr An integrated full-head OPM-MEG system based on 128 zero-field sensors
title_full_unstemmed An integrated full-head OPM-MEG system based on 128 zero-field sensors
title_short An integrated full-head OPM-MEG system based on 128 zero-field sensors
title_sort integrated full-head opm-meg system based on 128 zero-field sensors
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10303922/
https://www.ncbi.nlm.nih.gov/pubmed/37389367
http://dx.doi.org/10.3389/fnins.2023.1190310
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