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Real-Time Magnetocardiography with Passive Miniaturized Coil Array in Earth Ambient Field
We demonstrate a magnetocardiography (MCG) sensor that operates in non-shielded environments, in real-time, and without the need for an accompanying device to identify the cardiac cycles for averaging. We further validate the sensor’s performance on human subjects. Our approach integrates seven (7)...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10304140/ https://www.ncbi.nlm.nih.gov/pubmed/37420733 http://dx.doi.org/10.3390/s23125567 |
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author | Zhu, Keren Kiourti, Asimina |
author_facet | Zhu, Keren Kiourti, Asimina |
author_sort | Zhu, Keren |
collection | PubMed |
description | We demonstrate a magnetocardiography (MCG) sensor that operates in non-shielded environments, in real-time, and without the need for an accompanying device to identify the cardiac cycles for averaging. We further validate the sensor’s performance on human subjects. Our approach integrates seven (7) coils, previously optimized for maximum sensitivity, into a coil array. Based on Faraday’s law, magnetic flux from the heart is translated into voltage across the coils. By leveraging digital signal processing (DSP), namely, bandpass filtering and averaging across coils, MCG can be retrieved in real-time. Our coil array can monitor real-time human MCG with clear QRS complexes in non-shielded environments. Intra- and inter-subject variability tests confirm repeatability and accuracy comparable to gold-standard electrocardiography (ECG), viz., a cardiac cycle detection accuracy of >99.13% and averaged R-R interval accuracy of <5.8 ms. Our results confirm the feasibility of real-time R-peak detection using the MCG sensor, as well as the ability to retrieve the full MCG spectrum as based upon the averaging of cycles identified via the MCG sensor itself. This work provides new insights into the development of accessible, miniaturized, safe, and low-cost MCG tools. |
format | Online Article Text |
id | pubmed-10304140 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-103041402023-06-29 Real-Time Magnetocardiography with Passive Miniaturized Coil Array in Earth Ambient Field Zhu, Keren Kiourti, Asimina Sensors (Basel) Article We demonstrate a magnetocardiography (MCG) sensor that operates in non-shielded environments, in real-time, and without the need for an accompanying device to identify the cardiac cycles for averaging. We further validate the sensor’s performance on human subjects. Our approach integrates seven (7) coils, previously optimized for maximum sensitivity, into a coil array. Based on Faraday’s law, magnetic flux from the heart is translated into voltage across the coils. By leveraging digital signal processing (DSP), namely, bandpass filtering and averaging across coils, MCG can be retrieved in real-time. Our coil array can monitor real-time human MCG with clear QRS complexes in non-shielded environments. Intra- and inter-subject variability tests confirm repeatability and accuracy comparable to gold-standard electrocardiography (ECG), viz., a cardiac cycle detection accuracy of >99.13% and averaged R-R interval accuracy of <5.8 ms. Our results confirm the feasibility of real-time R-peak detection using the MCG sensor, as well as the ability to retrieve the full MCG spectrum as based upon the averaging of cycles identified via the MCG sensor itself. This work provides new insights into the development of accessible, miniaturized, safe, and low-cost MCG tools. MDPI 2023-06-14 /pmc/articles/PMC10304140/ /pubmed/37420733 http://dx.doi.org/10.3390/s23125567 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Zhu, Keren Kiourti, Asimina Real-Time Magnetocardiography with Passive Miniaturized Coil Array in Earth Ambient Field |
title | Real-Time Magnetocardiography with Passive Miniaturized Coil Array in Earth Ambient Field |
title_full | Real-Time Magnetocardiography with Passive Miniaturized Coil Array in Earth Ambient Field |
title_fullStr | Real-Time Magnetocardiography with Passive Miniaturized Coil Array in Earth Ambient Field |
title_full_unstemmed | Real-Time Magnetocardiography with Passive Miniaturized Coil Array in Earth Ambient Field |
title_short | Real-Time Magnetocardiography with Passive Miniaturized Coil Array in Earth Ambient Field |
title_sort | real-time magnetocardiography with passive miniaturized coil array in earth ambient field |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10304140/ https://www.ncbi.nlm.nih.gov/pubmed/37420733 http://dx.doi.org/10.3390/s23125567 |
work_keys_str_mv | AT zhukeren realtimemagnetocardiographywithpassiveminiaturizedcoilarrayinearthambientfield AT kiourtiasimina realtimemagnetocardiographywithpassiveminiaturizedcoilarrayinearthambientfield |