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Real-Time Magnetocardiography with Passive Miniaturized Coil Array in Earth Ambient Field

We demonstrate a magnetocardiography (MCG) sensor that operates in non-shielded environments, in real-time, and without the need for an accompanying device to identify the cardiac cycles for averaging. We further validate the sensor’s performance on human subjects. Our approach integrates seven (7)...

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Detalles Bibliográficos
Autores principales: Zhu, Keren, Kiourti, Asimina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10304140/
https://www.ncbi.nlm.nih.gov/pubmed/37420733
http://dx.doi.org/10.3390/s23125567
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author Zhu, Keren
Kiourti, Asimina
author_facet Zhu, Keren
Kiourti, Asimina
author_sort Zhu, Keren
collection PubMed
description We demonstrate a magnetocardiography (MCG) sensor that operates in non-shielded environments, in real-time, and without the need for an accompanying device to identify the cardiac cycles for averaging. We further validate the sensor’s performance on human subjects. Our approach integrates seven (7) coils, previously optimized for maximum sensitivity, into a coil array. Based on Faraday’s law, magnetic flux from the heart is translated into voltage across the coils. By leveraging digital signal processing (DSP), namely, bandpass filtering and averaging across coils, MCG can be retrieved in real-time. Our coil array can monitor real-time human MCG with clear QRS complexes in non-shielded environments. Intra- and inter-subject variability tests confirm repeatability and accuracy comparable to gold-standard electrocardiography (ECG), viz., a cardiac cycle detection accuracy of >99.13% and averaged R-R interval accuracy of <5.8 ms. Our results confirm the feasibility of real-time R-peak detection using the MCG sensor, as well as the ability to retrieve the full MCG spectrum as based upon the averaging of cycles identified via the MCG sensor itself. This work provides new insights into the development of accessible, miniaturized, safe, and low-cost MCG tools.
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spelling pubmed-103041402023-06-29 Real-Time Magnetocardiography with Passive Miniaturized Coil Array in Earth Ambient Field Zhu, Keren Kiourti, Asimina Sensors (Basel) Article We demonstrate a magnetocardiography (MCG) sensor that operates in non-shielded environments, in real-time, and without the need for an accompanying device to identify the cardiac cycles for averaging. We further validate the sensor’s performance on human subjects. Our approach integrates seven (7) coils, previously optimized for maximum sensitivity, into a coil array. Based on Faraday’s law, magnetic flux from the heart is translated into voltage across the coils. By leveraging digital signal processing (DSP), namely, bandpass filtering and averaging across coils, MCG can be retrieved in real-time. Our coil array can monitor real-time human MCG with clear QRS complexes in non-shielded environments. Intra- and inter-subject variability tests confirm repeatability and accuracy comparable to gold-standard electrocardiography (ECG), viz., a cardiac cycle detection accuracy of >99.13% and averaged R-R interval accuracy of <5.8 ms. Our results confirm the feasibility of real-time R-peak detection using the MCG sensor, as well as the ability to retrieve the full MCG spectrum as based upon the averaging of cycles identified via the MCG sensor itself. This work provides new insights into the development of accessible, miniaturized, safe, and low-cost MCG tools. MDPI 2023-06-14 /pmc/articles/PMC10304140/ /pubmed/37420733 http://dx.doi.org/10.3390/s23125567 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Zhu, Keren
Kiourti, Asimina
Real-Time Magnetocardiography with Passive Miniaturized Coil Array in Earth Ambient Field
title Real-Time Magnetocardiography with Passive Miniaturized Coil Array in Earth Ambient Field
title_full Real-Time Magnetocardiography with Passive Miniaturized Coil Array in Earth Ambient Field
title_fullStr Real-Time Magnetocardiography with Passive Miniaturized Coil Array in Earth Ambient Field
title_full_unstemmed Real-Time Magnetocardiography with Passive Miniaturized Coil Array in Earth Ambient Field
title_short Real-Time Magnetocardiography with Passive Miniaturized Coil Array in Earth Ambient Field
title_sort real-time magnetocardiography with passive miniaturized coil array in earth ambient field
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10304140/
https://www.ncbi.nlm.nih.gov/pubmed/37420733
http://dx.doi.org/10.3390/s23125567
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