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Personalizing Personalized Medicine: The Confluence of Pharmacogenomics, a Person’s Medication Experience and Ethics

Truly personalized precision medicine combines pharmacogenomics (PGx), a person’s lived medication experiences and ethics; person-centeredness lies at the confluence of these considerations. A person-centered perspective can help inform PGx-related treatment guidelines, shared decision-making for PG...

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Detalles Bibliográficos
Autores principales: Stratton, Timothy P., Olson, Anthony W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10304183/
https://www.ncbi.nlm.nih.gov/pubmed/37368427
http://dx.doi.org/10.3390/pharmacy11030101
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author Stratton, Timothy P.
Olson, Anthony W.
author_facet Stratton, Timothy P.
Olson, Anthony W.
author_sort Stratton, Timothy P.
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description Truly personalized precision medicine combines pharmacogenomics (PGx), a person’s lived medication experiences and ethics; person-centeredness lies at the confluence of these considerations. A person-centered perspective can help inform PGx-related treatment guidelines, shared decision-making for PGx-related therapeutics and PGx-related healthcare policy. This article examines the interplay between these components of person-centered PGx-related care. Ethics concepts addressed include privacy, confidentiality, autonomy, informed consent, fiduciary responsibility, respect, the burden of pharmacogenomics knowledge for both the patient and healthcare provider and the pharmacist’s ethical role in PGx-testing. Incorporating the patient’s lived medication experience and ethics principles into PGx-based discussions of treatment can optimize the ethical, person-centered application of PGx testing to patient care.
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spelling pubmed-103041832023-06-29 Personalizing Personalized Medicine: The Confluence of Pharmacogenomics, a Person’s Medication Experience and Ethics Stratton, Timothy P. Olson, Anthony W. Pharmacy (Basel) Review Truly personalized precision medicine combines pharmacogenomics (PGx), a person’s lived medication experiences and ethics; person-centeredness lies at the confluence of these considerations. A person-centered perspective can help inform PGx-related treatment guidelines, shared decision-making for PGx-related therapeutics and PGx-related healthcare policy. This article examines the interplay between these components of person-centered PGx-related care. Ethics concepts addressed include privacy, confidentiality, autonomy, informed consent, fiduciary responsibility, respect, the burden of pharmacogenomics knowledge for both the patient and healthcare provider and the pharmacist’s ethical role in PGx-testing. Incorporating the patient’s lived medication experience and ethics principles into PGx-based discussions of treatment can optimize the ethical, person-centered application of PGx testing to patient care. MDPI 2023-06-15 /pmc/articles/PMC10304183/ /pubmed/37368427 http://dx.doi.org/10.3390/pharmacy11030101 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Stratton, Timothy P.
Olson, Anthony W.
Personalizing Personalized Medicine: The Confluence of Pharmacogenomics, a Person’s Medication Experience and Ethics
title Personalizing Personalized Medicine: The Confluence of Pharmacogenomics, a Person’s Medication Experience and Ethics
title_full Personalizing Personalized Medicine: The Confluence of Pharmacogenomics, a Person’s Medication Experience and Ethics
title_fullStr Personalizing Personalized Medicine: The Confluence of Pharmacogenomics, a Person’s Medication Experience and Ethics
title_full_unstemmed Personalizing Personalized Medicine: The Confluence of Pharmacogenomics, a Person’s Medication Experience and Ethics
title_short Personalizing Personalized Medicine: The Confluence of Pharmacogenomics, a Person’s Medication Experience and Ethics
title_sort personalizing personalized medicine: the confluence of pharmacogenomics, a person’s medication experience and ethics
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10304183/
https://www.ncbi.nlm.nih.gov/pubmed/37368427
http://dx.doi.org/10.3390/pharmacy11030101
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