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High glucose promotes the progression of colorectal cancer by activating the BMP4 signaling and inhibited by glucagon-like peptide-1 receptor agonist

BACKGROUND: The detailed molecular mechanism between type 2 diabetes mellitus (T2DM) and colorectal cancer (CRC) is still uncertain. Bone morphogenetic protein 4 (BMP4) dysregulation is implicated in T2DM and CRC, respectively. This study aims to investigate whether BMP4 can mediate the interaction...

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Detalles Bibliográficos
Autores principales: Ma, Bingwei, Wang, Xingchun, Ren, Hui, Li, Yingying, Zhang, Haijiao, Yang, Muqing, Li, Jiyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10304216/
https://www.ncbi.nlm.nih.gov/pubmed/37370018
http://dx.doi.org/10.1186/s12885-023-11077-w

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