The Kappa Opioid Receptor Agonist 16-Bromo Salvinorin A Has Anti-Cocaine Effects without Significant Effects on Locomotion, Food Reward, Learning and Memory, or Anxiety and Depressive-like Behaviors

Kappa opioid receptor (KOR) agonists have preclinical antipsychostimulant effects; however, adverse side effects have limited their therapeutic development. In this preclinical study, conducted in Sprague Dawley rats, B6-SJL mice, and non-human primates (NHPs), we evaluated the G-protein-biased anal...

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Detalles Bibliográficos
Autores principales: van de Wetering, Ross, Ewald, Amy, Welsh, Susan, Kornberger, Lindsay, Williamson, Samuel E., McElroy, Bryan D., Butelman, Eduardo R., Prisinzano, Thomas E., Kivell, Bronwyn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10304272/
https://www.ncbi.nlm.nih.gov/pubmed/37375403
http://dx.doi.org/10.3390/molecules28124848

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