Rapid Construction of a Chloromethyl-Substituted Duocarmycin-like Prodrug

The construction of duocarmycin-like compounds is often associated with lengthy synthetic routes. Presented herein is the development of a short and convenient synthesis of a type of duocarmycin prodrug. The 1,2,3,6-tetrahydropyrrolo[3,2-e]indole-containing core is here constructed from commercially...

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Detalles Bibliográficos
Autores principales: Bengtsson, Christoffer, Gravenfors, Ylva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10304315/
https://www.ncbi.nlm.nih.gov/pubmed/37375372
http://dx.doi.org/10.3390/molecules28124818

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10304315/
https://www.ncbi.nlm.nih.gov/pubmed/37375372
http://dx.doi.org/10.3390/molecules28124818

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