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Rapid Construction of a Chloromethyl-Substituted Duocarmycin-like Prodrug
The construction of duocarmycin-like compounds is often associated with lengthy synthetic routes. Presented herein is the development of a short and convenient synthesis of a type of duocarmycin prodrug. The 1,2,3,6-tetrahydropyrrolo[3,2-e]indole-containing core is here constructed from commercially...
Autores principales: | Bengtsson, Christoffer, Gravenfors, Ylva |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10304315/ https://www.ncbi.nlm.nih.gov/pubmed/37375372 http://dx.doi.org/10.3390/molecules28124818 |
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