Cargando…

The Secretome of Mesenchymal Stromal Cells in Treating Intracerebral Hemorrhage: The First Step to Bedside

Intracerebral hemorrhage is an unmet medical need that often leads to the disability and death of a patient. The lack of effective treatments for intracerebral hemorrhage makes it necessary to look for them. Previously, in our proof-of-concept study (Karagyaur M et al. Pharmaceutics, 2021), we have...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dzhauari, Stalik, Basalova, Nataliya, Primak, Alexandra, Balabanyan, Vadim, Efimenko, Anastasia, Skryabina, Mariya, Popov, Vladimir, Velichko, Arkadiy, Bozov, Kirill, Akopyan, Zhanna, Malkov, Pavel, Stambolsky, Dmitry, Tkachuk, Vsevolod, Karagyaur, Maxim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10304333/ https://www.ncbi.nlm.nih.gov/pubmed/37376058 http://dx.doi.org/10.3390/pharmaceutics15061608

Ejemplares similares

MSC Secretome as a Promising Tool for Neuroprotection and Neuroregeneration in a Model of Intracerebral Hemorrhage
por: Karagyaur, Maxim, et al.
Publicado: (2021)

Urokinase-Type Plasminogen Activator Enhances the Neuroprotective Activity of Brain-Derived Neurotrophic Factor in a Model of Intracerebral Hemorrhage
por: Dzhauari, Stalik, et al.
Publicado: (2022)

A Novel Cre/lox71-Based System for Inducible Expression of Recombinant Proteins and Genome Editing
por: Karagyaur, Maxim, et al.
Publicado: (2022)

The Power of Gene Technologies: 1001 Ways to Create a Cell Model
por: Karagyaur, Maxim, et al.
Publicado: (2022)

Advances and Obstacles in Using CRISPR/Cas9 Technology for Non-Coding RNA Gene Knockout in Human Mesenchymal Stromal Cells
por: Basalova, Nataliya, et al.
Publicado: (2023)

Novel Potency Assay for MSC Secretome-Based Treatment of Idiopathic Male Infertility Employed Leydig Cells and Revealed Vascular Endothelial Growth Factor as a Promising Potency Marker
por: Monakova, Anna, et al.
Publicado: (2022)

Alpha1A- and Beta3-Adrenoceptors Interplay in Adipose Multipotent Mesenchymal Stromal Cells: A Novel Mechanism of Obesity-Driven Hypertension
por: Chechekhin, Vadim, et al.
Publicado: (2023)

Secretome of Mesenchymal Stromal Cells Prevents Myofibroblasts Differentiation by Transferring Fibrosis-Associated microRNAs within Extracellular Vesicles
por: Basalova, Nataliya, et al.
Publicado: (2020)

Mesenchymal stromal cells facilitate resolution of pulmonary fibrosis by miR-29c and miR-129 intercellular transfer
por: Nataliya, Basalova, et al.
Publicado: (2023)

Therapeutic Angiogenesis by a “Dynamic Duo”: Simultaneous Expression of HGF and VEGF165 by Novel Bicistronic Plasmid Restores Blood Flow in Ischemic Skeletal Muscle
por: Slobodkina, Ekaterina, et al.
Publicado: (2020)

A magic kick for regeneration: role of mesenchymal stromal cell secretome in spermatogonial stem cell niche recovery
por: Sagaradze, Georgy, et al.
Publicado: (2019)

Mesenchymal Stromal Cells as Critical Contributors to Tissue Regeneration
por: Sagaradze, Georgy D., et al.
Publicado: (2020)

Conditioned Medium from Human Mesenchymal Stromal Cells: Towards the Clinical Translation
por: Sagaradze, Georgy, et al.
Publicado: (2019)

Regenerative medicine for male infertility: A focus on stem cell niche injury models
por: Sagaradze, Georgy, et al.
Publicado: (2022)

Self-Organization Provides Cell Fate Commitment in MSC Sheet Condensed Areas via ROCK-Dependent Mechanism
por: Nimiritsky, Peter, et al.
Publicado: (2021)

Adipose-Derived Stem Cells Stimulate Regeneration of Peripheral Nerves: BDNF Secreted by These Cells Promotes Nerve Healing and Axon Growth De Novo
por: Lopatina, Tatiana, et al.
Publicado: (2011)

Correction: Adipose-Derived Stem Cells Stimulate Regeneration of Peripheral Nerves: BDNF Secreted by These Cells Promotes Nerve Healing and Axon Growth De Novo
por: Lopatina, Tatiana, et al.
Publicado: (2019)

Corrigendum: Declined adipogenic potential of senescent MSCs due to shift in insulin signaling and altered exosome cargo
por: Voynova, Elizaveta, et al.
Publicado: (2023)

Declined adipogenic potential of senescent MSCs due to shift in insulin signaling and altered exosome cargo
por: Voynova, Elizaveta, et al.
Publicado: (2022)

Cell Sheets from Adipose Tissue MSC Induce Healing of Pressure Ulcer and Prevent Fibrosis via Trigger Effects on Granulation Tissue Growth and Vascularization
por: Alexandrushkina, Natalya, et al.
Publicado: (2020)

Secretome of Multipotent Mesenchymal Stromal Cells as a Promising Treatment and for Rehabilitation of Patients with the Novel Coronaviral Infection
por: Efimenko, A. Yu., et al.
Publicado: (2021)

Practical Use of Immortalized Cells in Medicine: Current Advances and Future Perspectives
por: Voloshin, Nikita, et al.
Publicado: (2023)

Scar-Free Healing of Endometrium: Tissue-Specific Program of Stromal Cells and Its Induction by Soluble Factors Produced After Damage
por: Eremichev, Roman, et al.
Publicado: (2021)

Decreased Insulin Sensitivity in Telomerase-Immortalized Mesenchymal Stem Cells Affects Efficacy and Outcome of Adipogenic Differentiation in vitro
por: Kulebyakin, Konstantin, et al.
Publicado: (2021)

Functional Heterogeneity of Protein Kinase A Activation in Multipotent Stromal Cells
por: Tyurin-Kuzmin, Pyotr A., et al.
Publicado: (2020)

Data supporting that miR-92a suppresses angiogenic activity of adipose-derived mesenchymal stromal cells by down-regulating hepatocyte growth factor
por: Efimenko, Anastassia, et al.
Publicado: (2015)

Autologous Stem Cell Therapy: How Aging and Chronic Diseases Affect Stem and Progenitor Cells
por: Efimenko, Anastasia Yu., et al.
Publicado: (2015)

Potency Assays for Mesenchymal Stromal Cell Secretome-Based Products for Tissue Regeneration
por: Sagaradze, Georgy, et al.
Publicado: (2023)

Insulin, intracerebral glucose and bedside biochemical monitoring utilizing microdialysis
por: Nordström, Carl-Henrik
Publicado: (2008)

Activation of β-adrenergic receptors is required for elevated α1A-adrenoreceptors expression and signaling in mesenchymal stromal cells
por: Tyurin-Kuzmin, Pyotr A., et al.
Publicado: (2016)

Novel Potential Markers of Myofibroblast Differentiation Revealed by Single-Cell RNA Sequencing Analysis of Mesenchymal Stromal Cells in Profibrotic and Adipogenic Conditions
por: Grigorieva, Olga, et al.
Publicado: (2023)

Unveiling Mesenchymal Stromal Cells’ Organizing Function in Regeneration
por: Nimiritsky, Peter P., et al.
Publicado: (2019)

Mesenchymal Stromal Cell-Produced Components of Extracellular Matrix Potentiate Multipotent Stem Cell Response to Differentiation Stimuli
por: Novoseletskaya, Ekaterina, et al.
Publicado: (2020)

Portable, bedside, low-field magnetic resonance imaging for evaluation of intracerebral hemorrhage
por: Mazurek, Mercy H., et al.
Publicado: (2021)

Editorial: From bench to bedside, targeting secondary brain damage following intracerebral hemorrhage
por: Gao, Cheng, et al.
Publicado: (2022)

CRISPR/Cas9 nickase mediated targeting of urokinase receptor gene inhibits neuroblastoma cell proliferation
por: Rysenkova, Karina D., et al.
Publicado: (2018)

Downregulation of uPAR promotes urokinase translocation into the nucleus and epithelial to mesenchymal transition in neuroblastoma
por: Semina, Ekaterina V., et al.
Publicado: (2020)

Urokinase Receptor uPAR Downregulation in Neuroblastoma Leads to Dormancy, Chemoresistance and Metastasis
por: Shmakova, Anna A., et al.
Publicado: (2022)

Characterization of secretomes provides evidence for adipose-derived mesenchymal stromal cells subtypes
por: Kalinina, Natalia, et al.
Publicado: (2015)

Bedside Catheter Hematoma Evacuation in Vitamin K Antagonist-Related Intracerebral Hemorrhage: A Safe and Feasible Approach
por: Volbers, Bastian, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_jes7kvm8se1jdte9li4hf57b97