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Choline Regulates SOX4 through miR-129-5p and Modifies H3K27me3 in the Developing Cortex

Choline availability regulates neural progenitor cell proliferation and differentiation in the developing cerebral cortex. Here, we investigated the molecular mechanism underlying this process and demonstrated that choline regulates the transcription factor SOX4 in neural progenitor cells. Specifica...

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Detalles Bibliográficos
Autores principales: Paules, Evan M., Silva-Gomez, Jorge A., Friday, Walter B., Zeisel, Steve H., Trujillo-Gonzalez, Isis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10304412/
https://www.ncbi.nlm.nih.gov/pubmed/37375678
http://dx.doi.org/10.3390/nu15122774