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A Miniature Multi-Functional Photoacoustic Probe
Photoacoustic technology is a promising tool to provide morphological and functional information in biomedical research. To enhance the imaging efficiency, the reported photoacoustic probes have been designed coaxially involving complicated optical/acoustic prisms to bypass the opaque piezoelectric...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10304571/ https://www.ncbi.nlm.nih.gov/pubmed/37374854 http://dx.doi.org/10.3390/mi14061269 |
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author | Lin, Riqiang Zhang, Jiaming Gao, Wen Wang, Xiatian Lv, Shengmiao Lam, Kwok-Ho Gong, Xiaojing |
author_facet | Lin, Riqiang Zhang, Jiaming Gao, Wen Wang, Xiatian Lv, Shengmiao Lam, Kwok-Ho Gong, Xiaojing |
author_sort | Lin, Riqiang |
collection | PubMed |
description | Photoacoustic technology is a promising tool to provide morphological and functional information in biomedical research. To enhance the imaging efficiency, the reported photoacoustic probes have been designed coaxially involving complicated optical/acoustic prisms to bypass the opaque piezoelectric layer of ultrasound transducers, but this has led to bulky probes and has hindered the applications in limited space. Though the emergence of transparent piezoelectric materials helps to save effort on the coaxial design, the reported transparent ultrasound transducers were still bulky. In this work, a miniature photoacoustic probe with an outer diameter of 4 mm was developed, in which an acoustic stack was made with a combination of transparent piezoelectric material and a gradient-index lens as a backing layer. The transparent ultrasound transducer exhibited a high center frequency of ~47 MHz and a −6 dB bandwidth of 29.4%, which could be easily assembled with a pigtailed ferrule of a single-mode fiber. The multi-functional capability of the probe was successfully validated through experiments of fluid flow sensing and photoacoustic imaging. |
format | Online Article Text |
id | pubmed-10304571 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-103045712023-06-29 A Miniature Multi-Functional Photoacoustic Probe Lin, Riqiang Zhang, Jiaming Gao, Wen Wang, Xiatian Lv, Shengmiao Lam, Kwok-Ho Gong, Xiaojing Micromachines (Basel) Communication Photoacoustic technology is a promising tool to provide morphological and functional information in biomedical research. To enhance the imaging efficiency, the reported photoacoustic probes have been designed coaxially involving complicated optical/acoustic prisms to bypass the opaque piezoelectric layer of ultrasound transducers, but this has led to bulky probes and has hindered the applications in limited space. Though the emergence of transparent piezoelectric materials helps to save effort on the coaxial design, the reported transparent ultrasound transducers were still bulky. In this work, a miniature photoacoustic probe with an outer diameter of 4 mm was developed, in which an acoustic stack was made with a combination of transparent piezoelectric material and a gradient-index lens as a backing layer. The transparent ultrasound transducer exhibited a high center frequency of ~47 MHz and a −6 dB bandwidth of 29.4%, which could be easily assembled with a pigtailed ferrule of a single-mode fiber. The multi-functional capability of the probe was successfully validated through experiments of fluid flow sensing and photoacoustic imaging. MDPI 2023-06-19 /pmc/articles/PMC10304571/ /pubmed/37374854 http://dx.doi.org/10.3390/mi14061269 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Communication Lin, Riqiang Zhang, Jiaming Gao, Wen Wang, Xiatian Lv, Shengmiao Lam, Kwok-Ho Gong, Xiaojing A Miniature Multi-Functional Photoacoustic Probe |
title | A Miniature Multi-Functional Photoacoustic Probe |
title_full | A Miniature Multi-Functional Photoacoustic Probe |
title_fullStr | A Miniature Multi-Functional Photoacoustic Probe |
title_full_unstemmed | A Miniature Multi-Functional Photoacoustic Probe |
title_short | A Miniature Multi-Functional Photoacoustic Probe |
title_sort | miniature multi-functional photoacoustic probe |
topic | Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10304571/ https://www.ncbi.nlm.nih.gov/pubmed/37374854 http://dx.doi.org/10.3390/mi14061269 |
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